Nitrofur SR Capsule 50 mg contains Nitrofurantoin, a long-acting antibiotic used to treat and prevent urinary tract infections (UTIs). Its sustained-release (SR) formulation ensures gradual release of the drug, maintaining effective concentrations in the urinary tract for extended periods. Nitrofurantoin works by inhibiting bacterial enzymes essential for DNA, RNA, and protein synthesis, effectively eliminating susceptible bacteria and supporting urinary tract health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nitrofur SR Capsule 50 mg is indicated for:

• Treatment of acute urinary tract infections (UTIs)
• Prevention of recurrent UTIs
• Infections caused by bacteria such as Escherichia coli and Staphylococcus saprophyticus

Mechanism of Action

Nitrofurantoin interferes with bacterial enzyme systems required for the synthesis of DNA, RNA, and proteins. This action leads to bacterial cell death. Due to its rapid excretion into the urine, the drug achieves high concentrations in the urinary tract, directly targeting infection sites.

Dosage and Administration

• Usually taken as 50 mg once or twice daily, as prescribed by a physician
• Swallow the capsule whole with water; do not crush or chew
• Can be taken with food or milk to reduce stomach irritation
• Complete the full course even if symptoms improve

Benefits

• Sustained-release formulation ensures prolonged therapeutic effect
• Convenient dosing for adults and older children
• Effectively treats and prevents recurrent UTIs
• Maintains urinary tract health
• Reduces bacterial recurrence and promotes faster recovery

Possible Side Effects

Common side effects:

• Nausea or vomiting
• Mild diarrhea
• Loss of appetite

Rare but serious side effects:

• Allergic reactions (rash, itching, swelling)
• Pulmonary reactions (cough, difficulty breathing)
• Liver function abnormalities

Seek immediate medical attention if serious symptoms occur.

Precautions and Warnings

• Not recommended in patients with severe kidney impairment
• Use cautiously in elderly patients
• Avoid during late pregnancy due to risk of hemolytic anemia in newborns
• Take with food or milk to minimize gastrointestinal irritation
• Not suitable for systemic infections outside the urinary tract

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Nitrofurantoin may interact with:

• Antacids containing magnesium trisilicate (may reduce absorption)
• Urinary acidifiers
• Other nephrotoxic medications

Inform your healthcare provider about all medications you are taking.

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep the capsule in its original container until use
• Keep out of reach of children.