Olapar Tablet 100 mg contains Olaparib, an oral anticancer medicine belonging to the class of PARP (poly ADP-ribose polymerase) inhibitors. It is used as targeted therapy in certain types of cancers, especially those associated with BRCA gene mutations. Olaparib works by interfering with cancer cell DNA repair mechanisms, helping to slow or stop tumor growth.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Olaparib
• Strength: 100 mg per tablet

Mechanism of Action

Olaparib inhibits PARP enzymes, which play a key role in repairing damaged DNA in cells. Cancer cells with defective BRCA1 or BRCA2 genes rely heavily on PARP for survival. By blocking this repair pathway, Olaparib causes accumulation of DNA damage in cancer cells, leading to cell death while sparing most normal cells.

Indications

Olapar Tablet 100 mg is indicated for:

• Maintenance treatment of ovarian cancer
• Breast cancer with BRCA mutation
• Pancreatic cancer with germline BRCA mutation (in selected cases)
• Prostate cancer with homologous recombination repair gene mutations
• Other cancers as determined by an oncologist

Dosage and Administration

• Taken orally as prescribed by an oncologist
• Usually administered twice daily depending on treatment protocol
• Tablets should be swallowed whole with water
• Can be taken with or without food
• Treatment duration depends on response and tolerability

Benefits

• Targets cancer cells with specific genetic defects
• Helps delay cancer progression and recurrence
• Oral administration for patient convenience
• Improves progression-free survival in eligible patients

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Fatigue or weakness
• Anemia (low red blood cells)
• Loss of appetite
• Diarrhea
• Headache

Serious side effects may include bone marrow suppression and rare risk of secondary cancers. Regular monitoring is essential.

Precautions and Warnings

• Must be used under strict oncology supervision
• Regular blood tests are required (CBC monitoring)
• Not recommended during pregnancy or breastfeeding
• Use with caution in patients with liver or kidney impairment
• Inform the doctor about all current medications

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Olapar Tablet 100 mg (Olaparib) is a targeted cancer therapy used in the treatment of BRCA-mutated and other advanced cancers. It works by blocking DNA repair in cancer cells, helping to control disease progression under specialist supervision.