Oxima Plus Inhalation Capsule 110 mcg + 50 mcg combines Indacaterol, a long-acting β2-adrenergic agonist (LABA), with Glycopyrronium, a long-acting muscarinic antagonist (LAMA), for the maintenance treatment of chronic obstructive pulmonary disease (COPD). This dual bronchodilator therapy provides complementary mechanisms of action: Indacaterol relaxes airway smooth muscles, while Glycopyrronium inhibits bronchoconstriction mediated by acetylcholine. Oxima Plus delivers effective, once-daily bronchodilation, improving lung function, reducing symptoms, and enhancing quality of life in COPD patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Oxima Plus Inhalation Capsule is indicated for:

• Long-term maintenance treatment of moderate to severe chronic obstructive pulmonary disease (COPD)
• Relief of airflow obstruction, breathlessness, and wheezing
• Improvement of lung function, exercise tolerance, and overall quality of life
• Not for relief of acute bronchospasm or sudden COPD exacerbations

Mechanism of Action

Oxima Plus combines two active ingredients for synergistic bronchodilation:

• Indacaterol (110 mcg): Selectively stimulates β2-adrenergic receptors in airway smooth muscles, causing relaxation and sustained bronchodilation for up to 24 hours.
• Glycopyrronium (50 mcg): Blocks muscarinic M3 receptors in bronchial smooth muscle, preventing acetylcholine-induced bronchoconstriction.

Together, this combination provides enhanced airway dilation, reduces COPD symptoms, and improves respiratory function more effectively than monotherapy.

Dosage and Administration

• Adults: One 110 mcg + 50 mcg capsule inhaled once daily using a compatible dry powder inhaler
• Insert the capsule into the inhaler device and inhale deeply as instructed
• Capsules are for inhalation only and must not be swallowed
• Use at the same time each day for consistent symptom control
• Not suitable for immediate relief of acute bronchospasm; a short-acting bronchodilator should be used if needed

Benefits

• Provides 24-hour dual bronchodilation for effective symptom control
• Improves lung function, exercise capacity, and daily activity tolerance
• Reduces breathlessness and risk of COPD exacerbations
• Once-daily dosing enhances patient adherence and convenience
• Suitable for long-term maintenance therapy in moderate to severe COPD

Possible Side Effects

Oxima Plus Inhalation Capsule may cause:

• Cough or throat irritation after inhalation
• Headache, dizziness, or tremors
• Palpitations or increased heart rate
• Dry mouth due to Glycopyrronium
• Rare: arrhythmias, urinary retention, hypokalemia, or hypersensitivity reactions

Patients should report severe or persistent side effects to a healthcare provider.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not indicated for acute asthma attacks or sudden bronchospasm
• Use with caution in patients with cardiovascular disease, arrhythmias, glaucoma, or urinary retention
• Monitor for paradoxical bronchospasm
• Inform your doctor of all medications to avoid interactions
• Use under medical supervision during pregnancy or breastfeeding

Storage

• Store below 25°C in a cool, dry place
• Keep capsules in the original blister until use
• Protect from moisture and light
• Keep out of reach of children.