Phenadryl Syrup 10 mg/5 ml contains Diphenhydramine Hydrochloride, a first-generation antihistamine widely used for the relief of allergy symptoms, cold-related discomfort, and mild sleep disturbances. Diphenhydramine works by blocking histamine H1 receptors, reducing the effects of histamine in the body, which is responsible for allergic reactions such as itching, sneezing, and runny nose.

Phenadryl Syrup is formulated as a palatable, easy-to-administer liquid, making it suitable for children and adults who have difficulty swallowing tablets or capsules. It provides rapid relief from common allergic symptoms, helping patients regain comfort and improve quality of life.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Relieves allergic symptoms such as sneezing, runny nose, itchy eyes, and skin rashes

• Reduces nasal congestion and itching caused by seasonal or perennial allergies

• Provides relief from common cold symptoms

• Has mild sedative effects, helping with occasional sleep disturbances

• Oral syrup formulation ensures easy and accurate dosing for children and adults

• Fast-acting for prompt relief from discomfort

Mechanism of Action

Diphenhydramine Hydrochloride, the active ingredient in Phenadryl Syrup, acts as a competitive antagonist of histamine at H1 receptors:

1. Blocking Histamine Effects:

   • Histamine is released during allergic reactions and binds to H1 receptors, causing sneezing, itching, runny nose, and watery eyes.

   • Diphenhydramine blocks these receptors, preventing histamine from exerting its effects, thereby reducing allergic symptoms.

2. Mild Sedative Effect:

   • Being a first-generation antihistamine, Diphenhydramine crosses the blood-brain barrier, exerting a mild sedative effect that can help with short-term sleep difficulties.

3. Anti-Nausea and Motion Sickness Properties:

   • Diphenhydramine also has anticholinergic activity, which can reduce nausea, vomiting, and dizziness associated with motion sickness.

Indications

Phenadryl Syrup 10 mg/5 ml is indicated for:

• Relief of seasonal and perennial allergic rhinitis symptoms

• Management of urticaria (hives), itching, and skin rashes

• Symptomatic relief of common cold symptoms, including sneezing and runny nose

• Adjunct treatment for motion sickness or mild nausea

• Short-term relief for occasional sleep disturbances

Dosage and Administration

• Adults and Children over 12 years: 10–20 mg orally, 3–4 times daily, as needed.

• Children 6–12 years: 5–10 mg orally, 3–4 times daily, as recommended by a physician.

• Children under 6 years: Use only under medical supervision.

• Measure the dose accurately using a syringe or measuring cup.

• Can be taken with or without food. Avoid exceeding the recommended dose.

Precautions and Warnings

• May cause drowsiness; avoid driving or operating heavy machinery after administration.

• Use with caution in patients with glaucoma, asthma, urinary retention, or heart problems.

• Avoid alcohol or other sedatives while taking this medication.

• Not recommended during pregnancy or breastfeeding unless prescribed by a healthcare provider.

• Consult a physician if symptoms persist or worsen.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Phenadryl Syrup is generally well-tolerated. Possible side effects include:

• Drowsiness or sedation

• Dry mouth, nose, or throat

• Dizziness or mild gastrointestinal upset

• Rare: allergic reactions, confusion, or blurred vision

Storage

Store at 25°C in a cool, dry place, protected from light. Keep out of reach of children.

Phenadryl Syrup 10 mg/5 ml provides fast and effective relief from allergic symptoms, common cold discomfort, and mild sleep disturbances, making it a versatile choice for both children and adults.