Diapro MR Tablet 60 mg contains Gliclazide in a modified-release (MR) formulation, designed for the effective management of type 2 diabetes mellitus in adults. As a second-generation sulfonylurea, Gliclazide helps control blood glucose levels when diet, exercise, and lifestyle modifications alone do not provide adequate results. The modified-release technology allows the medicine to be released gradually over 24 hours, ensuring consistent glycemic control with convenient once-daily dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Gliclazide works by stimulating pancreatic beta cells to release insulin in response to increased blood glucose levels. It also enhances insulin sensitivity in peripheral tissues, improving glucose uptake by muscles and other cells. The MR formulation ensures a steady release of the drug, reducing sharp peaks in insulin secretion and helping to minimize fluctuations in blood sugar levels, which may lower the risk of hypoglycemia.

Indications

Diapro MR Tablet 60 mg is indicated for:

• Treatment of type 2 diabetes mellitus in adult patients

• Individuals who fail to achieve satisfactory blood glucose control with diet and exercise alone

• Use as monotherapy or in combination with other antidiabetic agents such as metformin, alpha-glucosidase inhibitors, or insulin, as prescribed by a physician

Dosage and Administration

The dosage of Diapro MR Tablet should be individualized according to the patient’s glycemic status and therapeutic response. It is usually taken once daily with breakfast. The tablet should be swallowed whole with a sufficient amount of water and must not be crushed or chewed, as this can interfere with the modified-release mechanism. Regular monitoring of blood glucose levels is recommended to ensure safe and effective treatment.

Benefits

• Provides sustained and stable blood glucose control throughout the day

• Once-daily dosing improves treatment adherence

• Helps reduce both fasting and postprandial blood sugar levels

• Lower risk of hypoglycemia when used as directed

• Supports prevention of long-term diabetes complications, including cardiovascular disease, neuropathy, nephropathy, and retinopathy

Possible Side Effects

Diapro MR Tablet is generally well tolerated. However, some patients may experience:

• Hypoglycemia, particularly if meals are skipped or excessive doses are taken

• Gastrointestinal disturbances such as nausea or abdominal discomfort

• Headache or dizziness

• Mild weight gain in some individuals

Severe hypoglycemia is rare but requires immediate medical attention if symptoms such as confusion, sweating, or palpitations occur.

Precautions and Warnings

• Use with caution in elderly patients and those with kidney or liver impairment

• Alcohol consumption may increase the risk of low blood sugar

• Not suitable for patients with type 1 diabetes or diabetic ketoacidosis

• Use during pregnancy and breastfeeding should be based on medical advice

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Diapro MR Tablet may interact with certain medicines, including beta-blockers, antifungal agents, anticoagulants, and some antibiotics. Patients should inform their healthcare provider about all medicines they are taking before starting treatment.

Storage

Store Diapro MR Tablet 60 mg in a cool, dry place away from direct sunlight. Keep out of reach of children.

Conclusion

Diapro MR Tablet 60 mg (Gliclazide) is an effective modified-release oral antidiabetic medicine that offers consistent, long-lasting blood glucose control for patients with type 2 diabetes mellitus. When combined with a healthy diet, regular exercise, and routine medical supervision, it plays an important role in achieving optimal glycemic control and improving overall quality of life.