Respira 1 mg/5 ml Syrup is a short-acting selective β2-adrenoceptor agonist designed to relieve and prevent bronchospasm in patients with reversible obstructive airway diseases. It is indicated for adults, adolescents, and children aged 6 years and older, providing fast and effective relief from airway constriction associated with asthma, chronic bronchitis, and other reversible airway disorders.

The active component is a single-isomer beta-2 agonist, which enhances bronchodilation while minimizing potential side effects associated with racemic formulations containing (S)-salbutamol. By targeting beta-2 adrenergic receptors in the bronchial smooth muscle, Respira promotes relaxation of bronchial muscle fibers, leading to improved airflow and relief of breathing difficulties.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Short-acting selective β2-adrenoceptor stimulants (bronchodilator)

Pharmacology and Mode of Action

Respira 1 mg/5 ml Syrup contains a single-isomer beta-2 agonist that works by:

• Stimulating beta-2 adrenergic receptors in the bronchial smooth muscle

• Relaxing bronchial muscle fibers, thereby dilating the airways

• Improving airflow in obstructed airways and preventing bronchospasm

Unlike racemic salbutamol, the elimination of (S)-salbutamol in Respira ensures that the bronchodilatory effect is not hindered, offering effective symptom control with a reduced risk of unwanted side effects.

Indications

Respira 1 mg/5 ml is indicated for:

• Treatment of bronchospasm in adults, adolescents, and children ≥6 years

• Prevention of bronchospasm associated with reversible obstructive airway diseases

• Relief of symptoms such as wheezing, shortness of breath, and tightness in the chest

Dosage and Administration

• Children (6–11 years): 5 ml (1 mg) three times daily

• Adolescents and Adults (>12 years): 5–10 ml (1–2 mg) three times daily

Administration Tips:

• Take orally, with or without food, as advised by the physician

• Follow strict adherence to the prescribed schedule to ensure effective management of symptoms

Drug Interactions

• Use caution when administered with other sympathomimetic bronchodilators or epinephrine

• Concomitant use of adrenergic drugs may increase cardiovascular effects such as palpitations or tremors

Contraindications

• Known hypersensitivity to Respira 1 mg/5 ml or any of its components

Side Effects

Common and uncommon adverse effects may include:

• Hypocalcemia

• Palpitations

• Fine skeletal muscle tremors

• Muscle cramps

• Gastrointestinal disturbances: nausea, vomiting, epigastric pain, diarrhea

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Use caution in acute severe asthma, especially in combination with hypoxia, xanthine derivatives, steroids, or diuretics

• Monitor serum potassium levels in at-risk patients

• Use during pregnancy only if benefits outweigh risks

• Exercise caution during breastfeeding, as excretion in human milk is unknown

Storage Conditions

• Store in a dry, cool place away from heat and light

• Keep out of reach of children

Respira 1 mg/5 ml Syrup provides fast, reliable relief from bronchospasm while minimizing side effects, making it an effective option for managing reversible obstructive airway diseases in children and adults.