Rizat Tablet 5 mg contains Rizatriptan Benzoate, a selective serotonin (5-HT1) receptor agonist used in the acute treatment of migraine attacks with or without aura in adults. Migraine is a neurological disorder characterized by recurrent, moderate-to-severe headaches often accompanied by nausea, vomiting, and sensitivity to light or sound. Rizatriptan works by narrowing dilated blood vessels in the brain and inhibiting the release of inflammatory neuropeptides, which are key contributors to migraine pain and associated symptoms.

Rizat provides rapid relief from migraine attacks, helping patients restore daily activities and improve quality of life. It is specifically designed for acute episodes and is not intended for prophylactic (preventive) therapy. The 5 mg dose offers an effective and well-tolerated option for adults with mild to moderate migraines or as an initial dose for new users.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Rizatriptan Benzoate 5 mg

• Excipients: Lactose monohydrate, microcrystalline cellulose, starch, magnesium stearate, and other standard tablet excipients

Indications

Rizat Tablet 5 mg is indicated for:

• Acute treatment of migraine attacks with or without aura in adults

• Relief of headache pain, nausea, photophobia, and phonophobia associated with migraines

• Rapid symptom control to restore daily functionality during migraine episodes

Mechanism of Action

Rizatriptan Benzoate works by:

• Agonizing 5-HT1B/1D receptors in cranial blood vessels, causing vasoconstriction and reducing vascular dilation associated with migraine

• Inhibiting the release of pro-inflammatory neuropeptides from trigeminal nerve endings, which contribute to pain and inflammation

• Reducing pain transmission and central sensitization, alleviating headache and associated symptoms

• Providing rapid onset of action, usually within 30–60 minutes, for effective relief

This dual action on blood vessels and nerve pathways makes Rizatriptan effective for acute migraine management.

Dosage and Administration

• Adults: 1 tablet (5 mg) taken orally at the onset of migraine symptoms

• May repeat the dose after 2 hours if the migraine persists, but do not exceed 2 doses (10 mg) in 24 hours

• Swallow the tablet whole with water; it can be taken with or without food

• Not recommended for prophylactic use or for headaches that are not diagnosed as migraines

• Patients with hepatic or renal impairment may require dose adjustment, as advised by a physician

Precautions and Warnings

• Do not use in patients with ischemic heart disease, uncontrolled hypertension, cerebrovascular disease, or peripheral vascular disease

• Avoid use in combination with MAO inhibitors or other triptans

• Use with caution in elderly patients or those with mild-to-moderate liver or kidney impairment

• Not recommended during pregnancy or breastfeeding without medical guidance

• Seek immediate medical attention if symptoms such as chest pain, shortness of breath, or severe dizziness occur

Possible Side Effects

Rizat Tablet 5 mg is generally well tolerated. Common side effects may include:

• Dizziness or drowsiness

• Tingling or flushing

• Nausea

• Fatigue

• Rarely, palpitations or transient chest discomfort

Most adverse effects are mild, short-lived, and resolve without intervention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Conclusion

Rizat Tablet 5 mg (Rizatriptan Benzoate) is an effective treatment for acute migraine attacks, offering rapid relief from headache, nausea, and sensitivity to light or sound. Its selective 5-HT1 receptor agonist action ensures targeted efficacy with minimal systemic effects. Proper use under medical supervision allows patients to manage migraine episodes effectively and maintain daily activities.