Rofurox Suspension 125 mg/5 ml (Cefuroxime Axetil) is an oral antibiotic commonly used to treat a variety of bacterial infections, particularly in children. It contains Cefuroxime Axetil, which belongs to the cephalosporin class of antibiotics. Cefuroxime axetil is a prodrug that converts into the active antibiotic cefuroxime in the body after absorption. The suspension form makes it easier for children and patients who have difficulty swallowing tablets to take the medicine.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition and Mechanism of Action

Rofurox Suspension contains cefuroxime axetil 125 mg per 5 ml. After ingestion, cefuroxime axetil is converted into cefuroxime, which works by interfering with the synthesis of the bacterial cell wall. Bacteria need a strong cell wall made mainly of peptidoglycan to survive and maintain their structure. Cefuroxime binds to specific enzymes called penicillin-binding proteins (PBPs) that are responsible for forming this cell wall.

By blocking these enzymes, cefuroxime prevents the proper formation of the bacterial cell wall. As a result, the bacterial cell becomes weak and eventually bursts, leading to bacterial death. This bactericidal mechanism makes cefuroxime effective against many Gram-positive and Gram-negative bacteria.

Indications

Rofurox Suspension 125 mg/5 ml is prescribed for the treatment of several infections caused by susceptible bacteria. It is commonly used to treat upper respiratory tract infections, including sinusitis, tonsillitis, and pharyngitis. It is also effective for lower respiratory tract infections such as bronchitis and pneumonia.

In pediatric patients, it is often used for ear infections (otitis media), which are very common among children. The suspension may also be prescribed for urinary tract infections (UTIs) affecting the bladder or kidneys. Additionally, it can be used to treat skin and soft tissue infections such as infected wounds, cellulitis, and impetigo.

In certain cases, cefuroxime may also be used in the treatment of early Lyme disease, particularly when the infection affects the skin.

Dosage and Administration

The dosage of Rofurox Suspension depends on the patient’s age, body weight, and severity of infection. In children, the dose is usually calculated based on body weight and is given twice daily as directed by a healthcare professional.

Before each use, the suspension should be shaken well to ensure the medication is evenly mixed. It is generally recommended to take the suspension after meals because food improves the absorption of cefuroxime and helps reduce stomach irritation. Parents should use a measuring spoon or syringe to ensure the correct dose is given.

It is very important to complete the full course of treatment even if the patient starts feeling better before the medication is finished. Stopping the antibiotic too early can lead to recurrence of infection and contribute to antibiotic resistance.

Side Effects

Like other antibiotics, Rofurox Suspension may cause some side effects. Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, or mild rash. These effects are usually temporary and mild.

Rare but serious side effects may include severe allergic reactions, persistent diarrhea caused by antibiotic-associated colitis, or changes in liver enzyme levels. Medical attention should be sought if symptoms such as difficulty breathing, swelling of the face or throat, or severe rash occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

Patients who have a known allergy to cephalosporin or penicillin antibiotics should inform their doctor before using this medication. Caution should also be exercised in patients with kidney disease, as dose adjustments may be required.

Pregnant or breastfeeding women should only use this medicine if recommended by a healthcare professional. Parents should carefully follow the dosage instructions to avoid overdosing.

Storage

Rofurox Suspension should be stored in a cool and dry place away from direct sunlight. After reconstitution, the suspension should be used within the time recommended by the manufacturer and kept out of the reach of children.