TAF Tablet 25 mg contains Tenofovir Alafenamide, an antiviral medicine used in the treatment of chronic Hepatitis B virus (HBV) infection. It belongs to the class of nucleotide reverse transcriptase inhibitors (NRTIs). TAF is a prodrug of tenofovir with improved stability and targeted delivery to liver cells, allowing effective viral suppression at a lower systemic exposure compared to older formulations.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tenofovir Alafenamide 25 mg

Mechanism of Action

Tenofovir Alafenamide is converted inside liver cells into its active form, tenofovir diphosphate. This active metabolite inhibits hepatitis B virus DNA polymerase (reverse transcriptase), which is essential for viral replication. By blocking this enzyme, it reduces viral multiplication and helps control chronic HBV infection.

Indications

TAF Tablet 25 mg is indicated for:

• Treatment of chronic Hepatitis B virus (HBV) infection in adults
• Patients with compensated liver disease requiring long-term antiviral therapy
• Viral suppression to reduce risk of liver complications such as cirrhosis and hepatocellular carcinoma

Dosage and Administration

• The usual recommended dose is 25 mg once daily.
• Should be taken with food for optimal absorption.
• Must be used regularly at the same time each day for best results.
• Dosage should be continued as prescribed by a physician; stopping abruptly may worsen hepatitis B infection.

Benefits

• Effective suppression of hepatitis B virus replication
• Lower risk of kidney and bone toxicity compared to older tenofovir formulations
• Once-daily oral dosing improves patient compliance
• Helps reduce progression of liver disease
• Suitable for long-term antiviral therapy

Side Effects

Common side effects may include:

• Headache
• Nausea
• Fatigue
• Abdominal discomfort
• Mild gastrointestinal upset

Rare but serious side effects may include worsening liver function after stopping treatment, kidney issues, or lactic acidosis. Medical supervision is required during therapy.

Precautions and Warnings

• Do not stop treatment without medical advice, as it may cause hepatitis B flare-up.
• Use cautiously in patients with kidney disease.
• Regular monitoring of liver and kidney function is recommended.
• Not a cure for hepatitis B; it controls viral replication.
• Inform your doctor if you are pregnant or breastfeeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

TAF Tablet may interact with:

• Other antiviral agents
• Nephrotoxic drugs (may affect kidney function)
• Certain anticonvulsants (may reduce effectiveness)
• Rifampin and similar enzyme inducers

Always inform your healthcare provider about all medications being taken.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.