Temozar Capsule 100 mg contains Temozolomide 100 mg, an oral alkylating chemotherapeutic agent used in the treatment of certain types of brain tumors. It is primarily indicated for the management of newly diagnosed and recurrent malignant gliomas, including glioblastoma multiforme and anaplastic astrocytoma.

Temozolomide is widely used as part of standard treatment protocols for brain cancer due to its ability to cross the blood-brain barrier effectively. It is commonly administered in combination with radiotherapy for newly diagnosed glioblastoma and as maintenance therapy thereafter. Temozar Capsule offers a convenient oral dosing option that supports patient compliance during long-term cancer treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Temozolomide 100 mg

Mechanism of Action

Temozolomide is an alkylating agent that works by damaging the DNA of cancer cells. After oral administration, it is rapidly converted into its active form in the body. The active metabolite interferes with DNA replication by adding alkyl groups to the DNA strands, leading to tumor cell death.

Because cancer cells divide rapidly, they are more susceptible to this DNA damage. By preventing tumor growth and spread, Temozar Capsule plays a crucial role in controlling disease progression.

Indications

Temozar Capsule 100 mg is indicated for:

• Newly diagnosed glioblastoma multiforme (in combination with radiotherapy, followed by maintenance therapy)

• Refractory or recurrent anaplastic astrocytoma

• Other malignant gliomas as prescribed by an oncologist

Treatment should always be initiated and supervised by a specialist experienced in oncology.

Dosage and Administration

• The dosage is determined by body surface area (BSA) and the specific treatment protocol.

• It is usually taken once daily for a defined treatment cycle, followed by a rest period.

• Capsules should be swallowed whole with water.

• It is recommended to take the medication on an empty stomach to reduce nausea.

Do not open, crush, or chew the capsule. Strict adherence to the prescribed schedule is essential for optimal therapeutic outcomes.

Benefits

• Effective oral chemotherapy option for brain tumors

• Crosses the blood-brain barrier efficiently

• Convenient capsule form for outpatient therapy

• Can be combined with radiotherapy for enhanced treatment outcomes

• Helps control tumor progression and improve survival rates

Precautions

• Regular blood count monitoring is required, as Temozolomide may cause bone marrow suppression.

• Use effective contraception during treatment and for a specified period after therapy.

• Avoid use during pregnancy unless clearly indicated.

• Caution is advised in patients with liver or kidney impairment.

Patients should report signs of infection, unusual bleeding, or persistent fatigue to their physician immediately.

Possible Side Effects

Common side effects may include:

• Nausea and vomiting

• Fatigue

• Loss of appetite

• Constipation

• Headache

Serious adverse effects may include:

• Low white blood cell count

• Thrombocytopenia

• Increased risk of infection

Medical supervision throughout the treatment course is essential.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 25°C

• Keep in a dry place

• Protect from light and moisture

• Keep out of reach of children

Temozar Capsule 100 mg is a clinically trusted chemotherapeutic agent designed to support comprehensive brain tumor management under specialized medical supervision.