Tiotrop Inhalation Capsule 18 mcg contains Tiotropium, a long-acting anticholinergic bronchodilator used in the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It works by relaxing the muscles in the airways, allowing them to remain open, which helps improve airflow, reduce breathlessness, and enhance the patient’s ability to perform daily activities.
Tiotropium provides once-daily symptom control and is not intended for relief of acute bronchospasm.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Indications
Tiotrop Inhalation Capsule is indicated for:
-
Maintenance treatment of chronic obstructive pulmonary disease (COPD)
-
Reduction of COPD exacerbations
-
Improvement of lung function and quality of life in patients with persistent airflow limitation
-
Management of symptoms associated with chronic bronchitis and emphysema
Mechanism of Action
Tiotropium is a long-acting muscarinic antagonist (LAMA) that:
-
Blocks muscarinic receptors (M1 and M3) in the airways
-
Inhibits acetylcholine-mediated bronchoconstriction
-
Relaxes airway smooth muscle, promoting sustained bronchodilation
-
Reduces mucus secretion in the airways, improving airflow
Its long duration of action allows for once-daily dosing, supporting consistent symptom management.
Dosage and Administration
-
Recommended dose: One 18 mcg inhalation capsule once daily using a dry powder inhaler.
-
Do not swallow the capsule; it is for inhalation only.
-
Insert the capsule into the inhaler device, pierce it, and inhale the powder deeply and steadily.
-
Exhale fully before inhaling and hold your breath for 5–10 seconds after inhalation.
-
Use at the same time each day for optimal effect.
-
Do not exceed the prescribed dose.
Benefits
-
Provides 24-hour bronchodilation for COPD management
-
Reduces shortness of breath and wheezing
-
Decreases frequency of COPD exacerbations
-
Improves exercise tolerance and daily activity performance
-
Convenient once-daily dosing enhances compliance
Side Effects
Common side effects may include:
-
Dry mouth
-
Throat irritation
-
Cough
-
Constipation
Serious but rare side effects:
-
Urinary retention
-
Glaucoma exacerbation
-
Allergic reactions (rash, swelling, difficulty breathing)
-
Rapid heartbeat (tachycardia)
Seek medical attention if severe reactions occur.
Precautions and Warnings
-
Not for acute asthma attacks or sudden breathlessness; use a short-acting rescue inhaler if needed.
-
Use with caution in patients with glaucoma, urinary retention, or prostatic hyperplasia.
-
Monitor for worsening respiratory symptoms.
-
Pregnancy and breastfeeding use only if clearly needed and under medical supervision.
-
Inform your healthcare provider of all medications, including over-the-counter drugs and supplements.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Drug Interactions
Tiotrop Inhalation Capsule may interact with:
-
Other anticholinergic medications (may increase side effects)
-
Beta-agonists (monitor for additive effects)
-
Drugs affecting heart rate or blood pressure
Always inform your physician about all medications being taken.
Storage
-
Store below 30°C in a cool, dry place
-
Protect from moisture and direct sunlight
-
Keep capsules in the blister pack until use
-
Keep out of reach of children.