Valporin CR Tablet 500 mg contains Sodium Valproate, a controlled-release formulation of a widely used anticonvulsant and mood stabilizer. It is primarily indicated for the treatment of epilepsy, bipolar disorder, and certain seizure-related conditions. The controlled-release (CR) formulation allows steady and prolonged release of the medication, ensuring stable blood levels, reduced dosing frequency, and improved patient compliance.

Valporin CR helps prevent seizure recurrence, manage manic or mixed episodes in bipolar disorder, and maintain neurological and psychiatric stability. It is particularly suitable for adults and older children who require long-acting therapy to improve symptom control and reduce fluctuations in drug levels.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effective Seizure Control: Reduces frequency and severity of generalized, partial, and absence seizures.

• Mood Stabilization: Manages manic and mixed episodes in bipolar disorder effectively.

• Controlled-Release Formulation: Ensures consistent drug levels for prolonged action and once-daily dosing convenience.

• Supports Long-Term Therapy: Safe and effective for extended use under medical supervision.

• Improves Quality of Life: Reduces seizure episodes and stabilizes mood, enhancing daily functioning.

Mechanism of Action

Sodium Valproate works by:

• Increasing gamma-aminobutyric acid (GABA) levels in the brain, which calms overactive neurons.

• Stabilizing electrical activity in neurons to prevent abnormal firing, thereby controlling seizures.

• Modulating neurotransmitter activity to help maintain mood stability in bipolar disorder.

The controlled-release formulation maintains steady plasma levels, reducing the risk of breakthrough seizures or mood fluctuations.

Indications

Valporin CR Tablet 500 mg is indicated for:

• Epilepsy: generalized, partial, and absence seizures

• Bipolar disorder: treatment and maintenance of manic episodes

• Migraine prophylaxis (as directed by a physician)

• Other neurological or psychiatric conditions requiring anticonvulsant therapy

Dosage and Administration

• Dosage is individualized according to age, weight, and clinical condition.

• Typically taken once or twice daily, as directed by the physician.

• Swallow the tablet whole; do not crush or chew.

• Take with or after meals to minimize gastrointestinal discomfort.

• Regular monitoring of liver function, blood counts, and plasma drug levels is recommended.

Precautions

• Avoid abrupt discontinuation to prevent seizure recurrence or mood destabilization.

• Use cautiously in patients with liver disease, kidney impairment, or history of pancreatitis.

• Inform your doctor of all other medications to avoid drug interactions.

• Pregnant or breastfeeding women should consult a physician before use.

• Report any unusual symptoms such as jaundice, persistent vomiting, or abdominal pain.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Nausea and mild gastrointestinal discomfort

• Tremors

• Weight gain

• Hair thinning

Rare but serious side effects include:

• Liver toxicity

• Pancreatitis

• Blood disorders (thrombocytopenia, anemia)

• Severe allergic reactions

Seek immediate medical attention if severe abdominal pain, jaundice, or unusual bleeding occurs.

Storage

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.