Viera Suspension 200 mg/5 ml contains Voriconazole, a broad-spectrum triazole antifungal agent used for the treatment of serious and potentially life-threatening fungal infections. This oral suspension formulation is especially useful for patients who have difficulty swallowing tablets or require flexible dosing, including pediatric and elderly patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Viera Suspension is indicated for:

• Invasive aspergillosis
• Candidemia (Candida bloodstream infections)
• Esophageal candidiasis
• Severe fungal infections resistant to other antifungal therapies
• Fungal infections in immunocompromised patients (e.g., cancer, transplant recipients)

Mechanism of Action

Voriconazole works by inhibiting the fungal cytochrome P450–dependent enzyme (14-alpha-sterol demethylase), which is essential for ergosterol synthesis. This leads to:

• Disruption of fungal cell membrane formation
• Increased membrane permeability
• Inhibition of fungal growth and replication
• Destruction of fungal cells

Dosage and Administration

• Taken orally as prescribed by a physician
• Usually administered every 12 hours after an initial loading dose
• Should be taken at least 1 hour before or 1 hour after meals
• Shake the bottle well before each use
• Measure the dose accurately using a proper measuring device
• Dosage is adjusted based on patient weight, age, and clinical condition

Benefits

• Effective against a wide range of serious fungal infections
• Suitable for patients who cannot swallow tablets
• Allows flexible and individualized dosing
• First-line therapy for invasive aspergillosis
• Useful for long-term antifungal treatment

Side Effects

Common side effects may include:

• Visual disturbances (blurred vision, sensitivity to light)
• Nausea and vomiting
• Headache
• Rash
• Elevated liver enzymes

Serious side effects:

• Liver toxicity
• Severe skin reactions and photosensitivity
• Cardiac rhythm disturbances
• Neurological symptoms (hallucinations, confusion)

Precautions and Warnings

• Regular monitoring of liver function is essential
• Avoid prolonged sun exposure due to photosensitivity risk
• Use cautiously in patients with liver disease
• Not recommended during pregnancy unless clearly necessary
• Monitor for visual and neurological side effects
• Dose adjustments may be required in renal or hepatic impairment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Viera Suspension may interact with:

• Rifampicin and other enzyme inducers
• Anticonvulsants (e.g., phenytoin)
• Warfarin (increased bleeding risk)
• Cyclosporine and tacrolimus (increased drug levels)
• Other medications metabolized by CYP450 enzymes

Consult a healthcare provider before combining with other drugs.

Storage

• Store below 30°C
• Protect from light and moisture
• Do not freeze
• Shake well before use
• Keep out of reach of children.