Vilsin 20 mg contains Avatrombopag, an oral thrombopoietin receptor agonist (TPO-RA) designed to increase platelet production in patients with thrombocytopenia. Thrombocytopenia, or low platelet count, can lead to serious bleeding risks, especially in patients with chronic liver disease or undergoing invasive procedures. Vilsin 20 mg stimulates the bone marrow to produce platelets naturally, offering a convenient and effective alternative to platelet transfusions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Avatrombopag 20 mg

• Dosage form: Oral tablet

Therapeutic Class

• Thrombopoietin receptor agonist

• Hematopoietic agent

Mechanism of Action

Avatrombopag works by selectively binding to and activating the thrombopoietin receptor (c-Mpl) on megakaryocyte precursors in the bone marrow. This activation promotes the proliferation and differentiation of megakaryocytes, leading to increased platelet production. By supporting the body’s own platelet synthesis, Vilsin 20 mg reduces the need for transfusions and lowers the risk of bleeding in patients with low platelet counts.

Indications

Vilsin 20 mg is indicated for:

• Thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a procedure, to reduce the risk of bleeding

• Treatment of chronic immune thrombocytopenia (ITP) in adults who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy

• Other thrombocytopenic conditions as determined by a healthcare professional

Dosage and Administration

• The dosage of Vilsin 20 mg is individualized according to platelet count, clinical condition, and treatment goals.

• Tablets should be taken orally, usually once daily, with or without food.

• To maximize absorption, avoid taking the tablet with products containing polyvalent cations (e.g., calcium, magnesium, aluminum, iron, or zinc) within 2–4 hours.

• Platelet counts should be monitored regularly to guide treatment duration and dose adjustments.

Benefits and Features

• Oral therapy avoids repeated platelet transfusions

• Supports safe platelet counts prior to invasive procedures

• Reduces bleeding risk in patients with chronic liver disease or ITP

• Convenient once-daily dosing improves patient adherence

• Promotes natural platelet production rather than relying on transfusions

Precautions and Warnings

• Monitor platelet counts closely to avoid excessive platelet elevation, which may increase the risk of thromboembolic events

• Liver function should be regularly assessed, especially in patients with chronic liver disease

• Use during pregnancy or breastfeeding only if clearly advised by a healthcare professional

• Patients should inform their doctor about all concomitant medications and supplements to avoid interactions

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects include headache, fatigue, nausea, and increased platelet counts. Rare but serious adverse effects may include thromboembolic events or hepatotoxicity, which require immediate medical attention.

Storage

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children

Vilsin 20 mg offers a reliable, targeted approach to managing thrombocytopenia. When used under medical supervision, it helps maintain safer platelet levels, reduces bleeding risk, and improves overall quality of life for patients at risk of low platelet complications.