Vistarin Injection 6000 Anti-Xa IU/0.6 ml contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) widely used for prevention and treatment of blood clots. It acts as an anticoagulant, inhibiting Factor Xa and thrombin, thereby reducing the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other thromboembolic conditions.
This higher-dose pre-filled syringe ensures accurate anticoagulation for patients requiring stronger therapeutic dosing, making it ideal for moderate to high-risk patients in surgical, cardiovascular, or medical settings.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Indications
Vistarin Injection 6000 Anti-Xa IU/0.6 ml is indicated for:
-
Prevention of venous thromboembolism (VTE) in high-risk surgical or hospitalized patients
-
Treatment of deep vein thrombosis (DVT) with or without pulmonary embolism (PE)
-
Management of acute coronary syndromes (ACS) to prevent further thrombus formation
-
Patients requiring therapeutic anticoagulation based on body weight or clinical need
Mechanism of Action
Enoxaparin Sodium works by:
-
Binding to antithrombin III, enhancing its ability to inactivate Factor Xa and partially Factor IIa (thrombin)
-
Preventing clot formation and propagation
-
Providing predictable anticoagulant effects with lower risk of heparin-induced thrombocytopenia (HIT) compared to unfractionated heparin
-
Reducing overall risk of thromboembolic events in both prophylactic and therapeutic settings
Dosage and Administration
-
Administered via subcutaneous injection, usually in the abdomen
-
Pre-filled syringe ensures accurate dosing of 6000 Anti-Xa IU/0.6 ml
-
Frequency and duration are determined by the patient’s condition, weight, and physician’s prescription
-
Avoid intramuscular injections to prevent hematoma formation
-
Rotate injection sites to minimize skin irritation
-
Monitor platelet count, renal function, and signs of bleeding during therapy
Benefits
-
Effectively prevents venous thromboembolism and pulmonary embolism
-
Treats deep vein thrombosis and acute coronary syndromes
-
Provides predictable anticoagulant activity, reducing the need for frequent laboratory monitoring
-
Lower risk of heparin-induced thrombocytopenia (HIT) compared to standard heparin
-
Pre-filled syringe ensures precise dosing and ease of use
Side Effects
Common side effects may include:
-
Mild injection site reactions such as pain, redness, or swelling
-
Minor bleeding or bruising
Serious but rare side effects:
-
Severe bleeding (internal or gastrointestinal)
-
Heparin-induced thrombocytopenia (HIT)
-
Allergic reactions (rash, swelling, difficulty breathing)
Seek immediate medical attention if severe bleeding or allergic reactions occur.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Precautions and Warnings
-
Use cautiously in patients with active bleeding, severe renal or liver disease, or low platelet count
-
Avoid combining with other anticoagulants or antiplatelet agents unless prescribed
-
Pregnancy and breastfeeding: use only under strict medical supervision
-
Regular monitoring of blood counts and coagulation parameters is advised
-
Contraindicated in patients with a history of heparin-induced thrombocytopenia (HIT)
Storage
-
Store at 2°C to 8°C (refrigerated)
-
Protect from light and freezing
-
Keep the syringe in its original packaging until use
-
Keep out of reach of children
-
Do not use after the expiration date.