Xadu Tablet 100 mg contains Roxadustat, a modern oral therapy indicated for the treatment of anemia associated with chronic kidney disease (CKD). Roxadustat is part of the advanced drug class known as hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs). It addresses the core pathophysiological mechanisms of CKD-related anemia by enhancing endogenous erythropoietin production and optimizing iron metabolism, offering an effective alternative to conventional injectable therapies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Roxadustat 100 mg

• Dosage form: Tablet

• Route of administration: Oral

Mechanism of Action

Roxadustat acts by inhibiting prolyl hydroxylase enzymes responsible for the degradation of hypoxia-inducible factors (HIFs). Stabilization of HIFs activates genes involved in erythropoiesis, leading to increased physiological production of erythropoietin in the kidneys and liver. In addition, Roxadustat lowers hepcidin levels, thereby improving intestinal iron absorption, mobilization of stored iron, and efficient hemoglobin synthesis. This dual action supports effective and sustained red blood cell production.

Indications

Xadu Tablet 100 mg is indicated for:

• Treatment of anemia in patients with chronic kidney disease

• Management of anemia in both dialysis-dependent and non-dialysis CKD patients, as directed by a physician

• Correction and maintenance of hemoglobin levels

• Reduction of anemia-related symptoms such as fatigue, shortness of breath, and reduced physical endurance

Dosage and Administration

The dosage of Xadu Tablet 100 mg should be individualized based on body weight, baseline hemoglobin levels, and patient response. It is administered orally at scheduled intervals as prescribed by a healthcare professional. The tablet should be swallowed whole with water and may be taken with or without food. Regular monitoring of hemoglobin, iron parameters, and overall clinical status is recommended during therapy.

Benefits and Key Features

• High-strength oral option for moderate to severe CKD-related anemia

• Stimulates natural erythropoietin production

• Enhances iron availability and utilization

• Helps maintain stable hemoglobin levels

• Reduces dependence on injectable erythropoiesis-stimulating agents

• Improves treatment convenience and patient compliance

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Xadu Tablet 100 mg is generally well tolerated when used under medical supervision. Potential side effects include headache, nausea, diarrhea, hypertension, hyperkalemia, and upper respiratory tract infections. Hemoglobin levels should be carefully monitored to avoid excessive increases. Caution is advised in patients with cardiovascular disease, liver impairment, or a history of thromboembolic events. Use during pregnancy and breastfeeding should only occur if clearly recommended by a healthcare professional.

Patients should inform their physician about all current medications and existing health conditions before starting treatment.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Xadu Tablet 100 mg from SK Pharma provides a powerful, convenient, and physiologically balanced approach to managing anemia in chronic kidney disease, supporting improved clinical outcomes and quality of life through advanced oral therapy.