Xelmet Tablet 500 mg contains Metformin Hydrochloride, an oral antidiabetic medicine widely used as a first-line treatment for type 2 diabetes mellitus. It helps control blood glucose levels by improving insulin sensitivity and reducing glucose production in the liver. Xelmet is commonly used alongside dietary control and regular exercise to achieve optimal glycemic management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Xelmet Tablet 500 mg is indicated for:

• Management of type 2 diabetes mellitus in adults
• Initial therapy in newly diagnosed diabetic patients
• Combination therapy with other oral antidiabetic agents or insulin
• Management of insulin resistance conditions such as polycystic ovary syndrome (PCOS), as prescribed

Mechanism of Action

Metformin lowers blood glucose levels through multiple mechanisms:

• Decreases hepatic glucose production (gluconeogenesis)
• Increases peripheral glucose uptake and utilization
• Improves insulin sensitivity in muscle and fat tissues
• Reduces intestinal absorption of glucose

It does not stimulate insulin secretion, which results in a low risk of hypoglycemia when used alone.

Dosage and Administration

• Dosage should be individualized based on blood glucose levels and physician guidance
• Usually taken 1–2 times daily with meals to reduce gastrointestinal discomfort
• Swallow the tablet whole with water
• Do not crush or chew unless advised by a healthcare professional
• Regular monitoring of blood glucose and kidney function is recommended

Benefits

• Effective first-line therapy for type 2 diabetes
• Helps reduce fasting and post-meal blood sugar levels
• Does not usually cause weight gain
• Low risk of hypoglycemia when used as monotherapy
• Can be combined with other antidiabetic medications for better control

Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort or bloating
• Loss of appetite
• Metallic taste

Rare but serious side effect:

• Lactic acidosis, especially in patients with kidney or liver impairment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal or hepatic impairment
• Avoid excessive alcohol consumption during treatment
• Temporary discontinuation may be required before contrast imaging procedures
• Not recommended in severe kidney dysfunction
• Regular monitoring of kidney function is essential

Storage

• Store below 25°C
• Protect from moisture and heat
• Keep out of reach of children.