Xelpid EZ Tablet 20 mg + 10 mg is a combination medicine containing Atorvastatin and Ezetimibe, used for the treatment of high cholesterol and mixed dyslipidemia. It is prescribed to reduce elevated LDL (bad cholesterol), total cholesterol, and triglycerides, while helping to improve HDL (good cholesterol) levels. This combination is especially useful in patients who require stronger lipid control than statin therapy alone can provide.

Atorvastatin works by reducing cholesterol production in the liver through inhibition of the HMG-CoA reductase enzyme. Ezetimibe works in the small intestine by blocking the absorption of cholesterol from dietary sources and bile. Together, they provide a dual mechanism that significantly enhances cholesterol reduction and cardiovascular protection.

Xelpid EZ Tablet is typically used along with lifestyle modifications such as a heart-healthy diet, regular physical activity, weight control, and smoking cessation. It helps reduce the long-term risk of cardiovascular events including heart attack and stroke in high-risk patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Atorvastatin Calcium USP equivalent to Atorvastatin 20 mg
• Ezetimibe USP 10 mg

Indications

Xelpid EZ Tablet is indicated for:

• Primary hypercholesterolemia
• Mixed dyslipidemia
• Familial hypercholesterolemia
• Patients not adequately controlled with statin monotherapy
• Prevention of cardiovascular events (heart attack and stroke)

How It Works

Atorvastatin inhibits the HMG-CoA reductase enzyme in the liver, reducing cholesterol synthesis. Ezetimibe blocks intestinal cholesterol absorption by inhibiting the NPC1L1 transporter. This dual action lowers both internally produced and dietary cholesterol levels.

Dosage and Administration

The dosage should be taken strictly as prescribed by a registered physician.

• Usual dose: 1 tablet once daily
• Can be taken with or without food
• Should be taken at the same time each day for best results
• Dose may be adjusted based on lipid profile and clinical response

Benefits of Xelpid EZ Tablet

• Dual mechanism for stronger cholesterol reduction
• Significantly lowers LDL cholesterol
• Improves overall lipid profile
• Reduces risk of heart attack and stroke
• Useful when statin alone is insufficient

Precautions

Use cautiously in:

• Liver disease or elevated liver enzymes
• Heavy alcohol use
• Kidney impairment
• Pregnancy and breastfeeding (contraindicated)
• History of muscle disorders or statin intolerance

Regular monitoring of liver function tests and lipid profile is recommended during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Muscle pain or weakness
• Headache
• Nausea
• Abdominal discomfort
• Fatigue
• Elevated liver enzymes

Rare but serious side effects include rhabdomyolysis and significant liver injury.

Storage

• Store below 30°C
• Protect from light and moisture
• Keep out of reach of children.