Xevirol Tablet 5 mg contains Everolimus, an immunosuppressant and targeted anticancer agent used in the treatment of certain cancers and in the prevention of organ transplant rejection. It belongs to the class of mTOR (mechanistic target of rapamycin) inhibitors, which help slow down abnormal cell growth and regulate immune system activity. This medication is typically prescribed and monitored by specialists in oncology or transplant medicine.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Xevirol Tablet 5 mg is indicated for:

• Advanced renal cell carcinoma (kidney cancer)
• Hormone receptor-positive, HER2-negative breast cancer (in combination therapy)
• Neuroendocrine tumors of pancreatic or gastrointestinal origin
• Prevention of organ rejection in kidney or liver transplant patients (as prescribed)
• Other malignancies as determined by a specialist

Mechanism of Action

Everolimus works by inhibiting the mTOR pathway, which plays a key role in cell growth, proliferation, and survival. By blocking this pathway:

• It slows down or stops the growth of cancer cells
• It reduces the formation of new blood vessels (angiogenesis) that tumors need to grow
• It suppresses immune responses, helping prevent organ transplant rejection

Dosage and Administration

• Dosage is determined by a specialist based on the condition being treated
• Usually taken once daily at the same time each day
• Swallow the tablet whole with water; do not crush or chew
• Can be taken with or without food, but consistency is important
• Regular monitoring of blood counts, kidney function, and drug levels may be required

Benefits

• Targeted therapy for specific types of cancers
• Helps slow tumor growth and progression
• Useful in both oncology and transplant medicine
• Provides immunosuppressive action to prevent organ rejection
• Oral administration for convenient long-term use

Side Effects

Common side effects may include:

• Mouth ulcers (stomatitis)
• Fatigue and weakness
• Rash
• Diarrhea
• Decreased appetite

Serious side effects:

• Increased risk of infections
• Lung inflammation (non-infectious pneumonitis)
• Kidney dysfunction
• Elevated blood sugar and cholesterol levels
• Bone marrow suppression (low blood cell counts)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Should be used only under specialist supervision
• Regular monitoring of blood counts and organ function is essential
• Avoid exposure to infections due to immunosuppressive effects
• Not recommended during pregnancy or breastfeeding
• May interact with many medications, including strong enzyme inhibitors or inducers
• Avoid grapefruit and grapefruit juice during treatment

Storage

• Store below 25°C
• Protect from moisture and light
• Keep out of reach of children.