Xidolac Injection 10 mg/ml contains Ketorolac Tromethamine, a potent non-steroidal anti-inflammatory drug (NSAID) used for the short-term management of moderate to severe acute pain. This injectable formulation provides rapid onset of analgesic action and is commonly used in hospital and clinical settings, especially when oral administration is not suitable. Xidolac Injection offers effective pain relief comparable to opioid analgesics, without the risk of dependence.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Indications

Xidolac Injection 10 mg/ml is indicated for the short-term treatment of moderate to severe pain, particularly in:

• Postoperative pain management

• Acute pain following trauma or injury

• Renal colic and severe musculoskeletal pain

• Acute gynecological or dental pain, as prescribed by a physician

This medicine is intended for short-term use only and is often followed by oral analgesics once pain is controlled.

Mechanism of Action

Ketorolac Tromethamine exerts its analgesic and anti-inflammatory effects by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes. These enzymes are responsible for the synthesis of prostaglandins, which mediate pain, inflammation, and swelling. By reducing prostaglandin production, Xidolac Injection effectively alleviates pain and inflammation, providing fast and reliable relief.

Dosage and Administration

Xidolac Injection 10 mg/ml should be administered only by qualified healthcare professionals.

• It may be given via intramuscular (IM) or intravenous (IV) injection, depending on clinical requirements.

• Dosage is individualized based on the patient’s age, weight, renal function, and severity of pain.

• The total duration of ketorolac therapy, including injectable and oral forms, should not exceed 5 days.

• Dose adjustments may be required in elderly patients or those with renal impairment.

Precautions and Warnings

• Xidolac Injection should be used with caution in patients with kidney disease, bleeding disorders, peptic ulcer disease, or cardiovascular risk factors.

• It should not be used in patients with active gastrointestinal bleeding or hypersensitivity to ketorolac or other NSAIDs.

• Concomitant use with other NSAIDs or anticoagulants increases the risk of bleeding and should be avoided unless strictly indicated.

• Use during pregnancy, especially in the third trimester, and breastfeeding is generally not recommended unless clearly advised by a physician.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

As with other NSAIDs, Xidolac Injection may cause side effects in some patients. Common side effects include:

• Nausea and vomiting

• Injection site pain or irritation

• Dizziness or headache

• Gastrointestinal discomfort

Rare but serious side effects such as gastrointestinal bleeding, kidney impairment, or severe allergic reactions require immediate medical attention.

Storage

Store Xidolac Injection 10 mg/ml in a cool, dry place below 30°C. Protect from light. Keep out of reach of children. Do not freeze.

Conclusion

Xidolac Injection 10 mg/ml is an effective and fast-acting option for short-term management of moderate to severe acute pain in clinical settings. When used appropriately under medical supervision, it provides strong analgesia while reducing the need for opioid medications.