Zemicef Capsule 400 mg contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic used for the treatment of a wide range of bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to bacterial destruction and effective resolution of infections. This higher-strength formulation is commonly used in moderate to severe infections or when a once-daily dosing regimen is preferred.

Zemicef 400 mg provides reliable broad-spectrum antibacterial coverage and is widely prescribed for respiratory, urinary, and gastrointestinal infections caused by susceptible organisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Zemicef Capsule 400 mg is indicated for the treatment of various bacterial infections, including:

• Upper respiratory tract infections such as tonsillitis and pharyngitis
• Lower respiratory tract infections including acute bronchitis
• Urinary tract infections (UTIs)
• Otitis media (middle ear infections)
• Uncomplicated gonorrhea
• Typhoid fever (as advised by a physician)
• Other bacterial infections caused by susceptible organisms

It is not effective against viral infections such as cold, flu, or COVID-19.

Mechanism of Action

Cefixime works through a bactericidal mechanism:

• Inhibits synthesis of bacterial cell wall
• Binds to penicillin-binding proteins (PBPs)
• Disrupts cell wall formation
• Causes bacterial cell lysis and death

This mechanism helps eliminate infection-causing bacteria and reduces symptoms such as fever, pain, and inflammation when used appropriately.

Dosage and Administration

• Dosage is determined by the physician based on infection type and severity.
• Commonly taken once daily or divided into two doses depending on clinical need.
• Can be taken with or without food; taking after meals may improve tolerance.
• Swallow the capsule whole with water.
• Complete the full course of therapy even if symptoms improve early.
• Do not skip doses or discontinue without medical advice to prevent antibiotic resistance.

Possible Side Effects

Some patients may experience mild to moderate side effects, including:

• Diarrhea
• Nausea or vomiting
• Abdominal discomfort
• Headache
• Indigestion
• Skin rash or allergic reactions

Seek immediate medical attention if severe allergic reactions, persistent diarrhea, or unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use cautiously in patients with known allergy to cephalosporins or penicillins.
• Dose adjustment may be required in renal impairment.
• Avoid misuse or unnecessary use to prevent antibiotic resistance.
• Inform the physician about all concurrent medications.
• Use during pregnancy and breastfeeding only under medical supervision.

Storage Conditions

• Store below 25°C in a cool, dry place
• Protect from moisture and direct sunlight
• Keep in original packaging
• Keep out of reach of children.