Acilog Mix SC Injection 30%+70% contains Biphasic Insulin Aspart, a combination of 30% rapid-acting insulin aspart and 70% intermediate-acting protamine-crystallized insulin aspart. This formulation provides both immediate postprandial glucose control and prolonged basal coverage, mimicking the body’s natural insulin secretion pattern. Acilog Mix is indicated for adults and children with diabetes mellitus who require effective glycemic management in a simplified regimen, reducing the number of daily injections while maintaining blood glucose stability.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Acilog Mix SC Injection 30%+70% is indicated for:

• Management of type 1 diabetes mellitus in adults and children
• Management of type 2 diabetes mellitus when diet, exercise, and oral antidiabetic therapy are insufficient
• Postprandial and basal glucose control in insulin-requiring patients
• Simplified insulin regimen for patients needing both rapid and intermediate action in a single injection

Mechanism of Action

• Rapid-Acting Insulin Aspart (30%): Lowers blood glucose quickly by promoting glucose uptake into muscle and fat tissues and suppressing hepatic glucose production. This component addresses post-meal blood sugar spikes.
• Intermediate-Acting Protamine-Crystallized Insulin Aspart (70%): Provides a sustained insulin effect, maintaining basal glucose control between meals and overnight.

The combination ensures effective overall glycemic management with fewer injections, balancing rapid and extended insulin action.

Dosage and Administration

• Administer subcutaneously in the thigh, abdomen, or upper arm.
• Typically injected 30 minutes before meals, or as advised by a healthcare professional.
• Dosage must be individualized based on blood glucose monitoring, diet, activity, and other medications.
• Rotate injection sites to prevent lipodystrophy or localized skin reactions.
• Do not inject intravenously or intramuscularly unless directed by a physician.

Side Effects

Common side effects include:

• Hypoglycemia – symptoms include dizziness, sweating, trembling, or confusion
• Injection site reactions – redness, swelling, or itching
• Mild weight gain

Rare but serious side effects:

• Severe hypoglycemia leading to unconsciousness or seizures
• Allergic reactions – rash, swelling, or anaphylaxis
• Lipodystrophy or localized fat changes at repeated injection sites

Seek immediate medical attention for severe hypoglycemia or allergic reactions.

Precautions and Warnings

• Frequent blood glucose monitoring is essential to prevent hypoglycemia or hyperglycemia.
• Use with caution in patients with kidney or liver impairment.
• Inform your doctor if pregnant, breastfeeding, or planning pregnancy.
• Carry fast-acting carbohydrates to manage low blood sugar episodes.
• Avoid skipping meals after injection to prevent hypoglycemia.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Acilog Mix may interact with:

• Oral antidiabetic drugs – dosage adjustments may be needed
• Beta-blockers – may mask hypoglycemia symptoms
• Corticosteroids – may increase blood glucose levels
• Alcohol – may unpredictably affect glucose control

Always inform your healthcare provider about all concurrent medications.

Storage Instructions

• Store unopened vials or pens in a refrigerator at 2–8°C
• Do not freeze
• Protect from direct sunlight and heat
• Once opened, keep at room temperature (below 30°C) and use within 28 days
• Keep out of reach of children.