Atanib Tablet 40 mg contains Afatinib Dimaleate, an oral tyrosine kinase inhibitor (TKI) used for the treatment of specific types of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. Afatinib is a targeted anticancer therapy that works by irreversibly blocking the activity of the ErbB family of receptors, including EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4), thereby slowing or stopping the growth and spread of cancer cells.

Atanib Tablet is primarily prescribed for adult patients with metastatic NSCLC whose tumors have specific EGFR mutations identified through validated diagnostic testing. Unlike conventional chemotherapy, Afatinib targets the molecular abnormalities that drive cancer growth, offering a more personalized approach to treatment. In selected patients, it can help delay disease progression, improve symptom control, and enhance quality of life.

Because Afatinib is a potent anticancer medicine, treatment should be initiated and monitored by an oncologist experienced in the use of targeted therapies. Regular follow-up and laboratory monitoring are essential to evaluate treatment response and manage potential side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Atanib Tablet 40 mg is indicated for:

• First-line treatment of adults with metastatic non-small cell lung cancer (NSCLC) harboring susceptible EGFR mutations.
• Treatment of metastatic squamous NSCLC that has progressed after platinum-based chemotherapy, where clinically appropriate.
• Other approved indications as determined by the treating oncologist and current clinical guidelines.

How Atanib Tablet Works

Afatinib is an irreversible ErbB family blocker that inhibits the signaling pathways responsible for cancer cell growth and survival. By permanently binding to EGFR, HER2, and HER4 receptors, it prevents the activation of proteins involved in tumor proliferation, angiogenesis, and metastasis. This targeted action slows the growth of cancer cells and may reduce tumor progression in patients with EGFR mutation-positive NSCLC.

Benefits of Atanib Tablet 40 mg

• Specifically targets EGFR mutation-positive lung cancer cells.
• Helps slow the progression of non-small cell lung cancer.
• May reduce tumor growth and improve disease control.
• Oral tablet formulation for convenient daily administration.
• Provides a targeted treatment approach compared with conventional chemotherapy.
• May improve progression-free survival in eligible patients.
• Supports personalized cancer treatment based on genetic testing.

Dosage and Administration

Take Atanib Tablet 40 mg exactly as prescribed by your oncologist. It is usually taken once daily on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the tablet whole with water and take it at approximately the same time each day.

The dosage may be adjusted based on individual response, tolerability, and the occurrence of adverse effects. Do not change the dose or discontinue treatment unless instructed by your healthcare provider.

Possible Side Effects

Like all medicines, Atanib Tablet may cause side effects, although not everyone experiences them.

Common side effects include:

• Diarrhea
• Skin rash or acne-like eruption
• Dry skin
• Mouth sores (stomatitis)
• Nail inflammation (paronychia)
• Decreased appetite
• Fatigue

Serious side effects may include:

• Severe diarrhea leading to dehydration
• Interstitial lung disease or pneumonitis
• Liver function abnormalities
• Severe skin reactions
• Eye disorders such as keratitis
• Impaired heart function (rare)

Seek immediate medical attention if you experience severe diarrhea, persistent cough, difficulty breathing, chest pain, vision changes, or signs of liver problems such as yellowing of the skin or eyes.

Precautions and Warnings

Before taking Atanib Tablet, inform your healthcare provider if you have:

• Lung disease or breathing problems
• Liver or kidney impairment
• Heart disease
• Eye disorders
• A history of severe skin reactions
• Pregnancy or plans to become pregnant
• Breastfeeding

Women of childbearing potential should use effective contraception during treatment and for the recommended period after the last dose. Regular monitoring of liver function, kidney function, and overall clinical status is recommended throughout treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from moisture and direct sunlight. Keep the tablets in their original packaging and out of the reach of children.

Disclaimer

Atanib Tablet 40 mg is a prescription-only anticancer medicine and should be used only under the supervision of a qualified oncologist. Do not self-medicate or share this medicine with others. Regular medical follow-up and laboratory monitoring are essential to ensure safe and effective treatment.