Azelec Cream 20% is a topical dermatological preparation containing Azelaic Acid 20%, widely used in the management of acne vulgaris, rosacea, and hyperpigmentation disorders. Azelaic acid is a naturally occurring dicarboxylic acid known for its antimicrobial, anti-inflammatory, and keratolytic properties. Azelec Cream is suitable for long-term use and is effective for patients with sensitive skin when used as directed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Azelaic Acid

• Strength: 20% w/w

• Dosage Form: Topical cream

Therapeutic Class

• Topical anti-acne agent

• Keratolytic and antibacterial agent

Indications

Azelec Cream 20% is indicated for the treatment of:

• Acne vulgaris, including mild to moderate inflammatory and non-inflammatory acne

• Rosacea, particularly papulopustular rosacea

• Hyperpigmentation disorders such as melasma and post-inflammatory hyperpigmentation

• Uneven skin tone associated with excessive melanin production

It helps reduce acne lesions, redness, and pigmentation while improving overall skin texture.

Pharmacology

Azelaic acid exerts its therapeutic effects through multiple mechanisms:

• It has antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis, the bacteria commonly associated with acne.

• It normalizes keratinization of the follicular epithelium, preventing the formation of comedones.

• Its anti-inflammatory properties help reduce redness, swelling, and irritation seen in acne and rosacea.

• Azelaic acid also inhibits tyrosinase, an enzyme involved in melanin synthesis, which helps reduce abnormal pigmentation and promotes a more even skin tone.

Due to minimal systemic absorption, Azelec Cream is considered safe for topical use when applied to intact skin.

Directions for Use

• Clean and dry the affected area before application.

• Apply a thin layer of Azelec Cream to the affected skin twice daily or as directed by a physician.

• Gently massage until fully absorbed.

• Avoid contact with eyes, mouth, and mucous membranes.

• Visible improvement may take several weeks; continued use is recommended for optimal results.

Side Effects

Azelec Cream is generally well tolerated. Some patients may experience:

• Mild burning or stinging sensation

• Itching or tingling

• Dryness or peeling of the skin

• Redness at the application site

These effects are usually mild and transient, especially during the initial phase of treatment.

Precautions and Warnings

• For external use only.

• Avoid use on broken or irritated skin.

• If severe irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

• Use sunscreen during the day to protect the skin from UV exposure, especially when treating hyperpigmentation.

• Use during pregnancy or breastfeeding only under medical advice.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

No significant drug interactions have been reported with topical azelaic acid. However, concurrent use with other topical agents should be done cautiously to avoid skin irritation.

Storage Conditions

• Store below 30°C

• Protect from excessive heat and light

• Keep the tube tightly closed

• Keep out of reach of children.