Co-Valtin Tablet 5 mg + 80 mg is a fixed-dose combination of Amlodipine Besilate, a calcium channel blocker, and Valsartan, an angiotensin II receptor blocker (ARB). This combination is designed for the effective management of hypertension (high blood pressure) in patients who require more than one antihypertensive agent to achieve optimal blood pressure control. By acting through two complementary mechanisms, Co-Valtin Tablet helps reduce blood pressure while improving cardiovascular outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amlodipine Besilate: 5 mg

• Valsartan: 80 mg

• Dosage Form: Film-coated tablet

• Route of Administration: Oral

Mechanism of Action

Amlodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, leading to relaxation of blood vessels and reduced peripheral resistance. This results in improved blood flow and lower blood pressure.
Valsartan selectively blocks angiotensin II receptors, preventing vasoconstriction and reducing aldosterone secretion. This leads to vasodilation, decreased sodium and water retention, and further reduction in blood pressure. The combined action provides enhanced antihypertensive efficacy with good tolerability.

Indications

Co-Valtin Tablet 5 mg + 80 mg is indicated for:

• Treatment of essential hypertension

• Management of blood pressure in patients inadequately controlled on monotherapy

• Reduction of cardiovascular risk associated with uncontrolled hypertension

It is suitable for long-term use under medical supervision.

Dosage and Administration

• The usual recommended dose is one tablet once daily, or as prescribed by a physician.

• The tablet should be swallowed whole with water and may be taken with or without food.

• Dosage adjustments may be required based on patient response and clinical condition.

Patients are advised to take the medicine at the same time each day to maintain consistent blood pressure control.

Contraindications

Co-Valtin Tablet is contraindicated in:

• Patients with known hypersensitivity to amlodipine, valsartan, or any component of the formulation

• Severe hepatic impairment or biliary obstruction

• Pregnancy, especially during the second and third trimesters

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal impairment or volume depletion

• Blood pressure, kidney function, and electrolyte levels should be monitored regularly

• Dizziness may occur, especially at the start of therapy

Possible Side Effects

Common side effects may include:

• Dizziness or headache

• Peripheral edema

• Fatigue

Less common effects include gastrointestinal discomfort and hypotension.

Storage

Store below 30°C in a cool and dry place. Protect from light and moisture. Keep out of reach of children.

Conclusion

Co-Valtin Tablet 5 mg + 80 mg offers an effective and convenient dual-action approach to hypertension management. Its complementary mechanisms help achieve better blood pressure control and support long-term cardiovascular health when used under proper medical guidance.