Corabid Tablet 5 mg contains Ivabradine 5 mg, a selective heart rate-lowering agent used in the management of chronic stable angina and certain cases of chronic heart failure. Ivabradine works by specifically reducing the heart rate without affecting blood pressure or the strength of heart contractions, making it a valuable option for patients who require heart rate control.

In conditions such as chronic stable angina, the heart requires more oxygen than it receives, leading to chest pain and discomfort. By lowering the heart rate, Ivabradine reduces the heart’s oxygen demand and improves exercise tolerance. In chronic heart failure, an elevated heart rate can worsen symptoms and increase the risk of complications. Ivabradine helps reduce hospitalization rates and improves overall cardiac function in eligible patients.

Unlike beta-blockers, Ivabradine acts selectively on the sinoatrial (SA) node—the natural pacemaker of the heart—by inhibiting the “funny” (If) current responsible for regulating heart rhythm. This targeted mechanism allows effective heart rate reduction without significantly impacting blood pressure or myocardial contractility.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Corabid Tablet 5 mg is indicated for:

• Chronic stable angina in patients with normal sinus rhythm

• Chronic heart failure with reduced ejection fraction

• Patients intolerant to or inadequately controlled by beta-blockers

Key Benefits

• Effectively lowers resting heart rate

• Reduces frequency and severity of angina attacks

• Improves exercise capacity

• Decreases risk of hospitalization in chronic heart failure

• Selective action with minimal effect on blood pressure

Mechanism of Action

Ivabradine selectively inhibits the If (funny) current in the sinoatrial node. This slows the spontaneous pacemaker activity of the heart, resulting in a reduced heart rate. By decreasing heart rate, it lowers myocardial oxygen consumption and improves diastolic filling time, enhancing cardiac efficiency.

Dosage and Administration

The dosage of Corabid Tablet 5 mg should be determined by a healthcare professional based on the patient’s condition and heart rate response. It is usually taken twice daily with meals.

Dose adjustments may be made according to resting heart rate and clinical response. Tablets should be swallowed whole with water. Regular monitoring of heart rate is recommended during treatment.

Precautions

• Not recommended in patients with severe bradycardia or certain heart rhythm disorders.

• Use cautiously in patients with low blood pressure.

• Avoid use during pregnancy unless clearly indicated.

• Monitor heart rate regularly during therapy.

• Inform the physician about any other cardiac medications being taken.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Bradycardia (slow heart rate)

• Visual disturbances (temporary brightness in vision)

• Dizziness

• Fatigue

• Headache

Most side effects are mild and manageable with proper dose adjustment.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.