Dialiptin-M Tablet 50 mg+500 mg is a combination oral antidiabetic medication containing Vildagliptin 50 mg and Metformin Hydrochloride 500 mg, formulated for effective management of type 2 diabetes mellitus. This dual-action therapy targets two critical aspects of blood glucose regulation: enhancing insulin secretion and reducing hepatic glucose production. Dialiptin-M provides an integrated approach for adults whose blood sugar levels are not adequately controlled by lifestyle measures or monotherapy with either Vildagliptin or Metformin alone.

Vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases the activity of incretin hormones, which stimulate insulin release after meals and suppress glucagon secretion. This helps regulate postprandial and fasting blood glucose levels. Metformin Hydrochloride, a biguanide, works by decreasing glucose production in the liver, improving insulin sensitivity, and enhancing peripheral glucose uptake. Together, these agents provide complementary effects for optimal glycemic control, addressing both insulin deficiency and insulin resistance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dialiptin-M Tablet 50 mg+500 mg is indicated for adult patients with type 2 diabetes mellitus:

• When diet, exercise, and monotherapy are insufficient to achieve glycemic targets

• As part of combination therapy with other antidiabetic agents when needed

• For patients who benefit from dual-action therapy targeting both insulin secretion and insulin resistance

This combination is not suitable for type 1 diabetes or diabetic ketoacidosis.

Dosage and Administration

The dosage of Dialiptin-M Tablet 50 mg+500 mg should be individualized based on the patient’s clinical condition, renal function, and blood glucose levels:

• Typically administered once or twice daily with meals to reduce gastrointestinal side effects

• Swallow the tablet whole with water; do not crush or chew

• Monitor blood glucose regularly to assess efficacy

• Maintain adherence to diet, exercise, and lifestyle interventions to optimize results

Patients should follow the physician’s instructions carefully and should not adjust the dose independently.

Precautions

• Contraindicated in patients with hypersensitivity to Vildagliptin, Metformin, or any excipients

• Use cautiously in patients with kidney or liver impairment; regular monitoring of renal and hepatic function is recommended

• Temporarily discontinue therapy during severe infections, dehydration, or major surgical procedures

• Risk of hypoglycemia may increase when combined with insulin or sulfonylureas

• Inform the physician of all ongoing medications and health conditions to prevent interactions

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dialiptin-M Tablet 50 mg+500 mg is generally well tolerated. Common side effects may include:

• Gastrointestinal issues such as nausea, vomiting, or diarrhea

• Mild headache or dizziness

• Hypoglycemia, particularly with concomitant insulin or sulfonylurea therapy

• Rare risk of lactic acidosis (related to Metformin)

Seek immediate medical attention if severe abdominal pain, rapid breathing, fatigue, or signs of allergic reaction occur.

Storage

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Dialiptin-M Tablet 50 mg+500 mg offers a safe and effective dual-action approach to managing type 2 diabetes mellitus, supporting better glycemic control and reducing the risk of long-term complications.