Evania M Tablet 12.5 mg + 500 mg is a combination oral antidiabetic medication that contains Empagliflozin and Metformin Hydrochloride. It is used for the treatment of type 2 diabetes mellitus, especially in patients who require combination therapy for better glycemic control.

This formulation offers a balanced dose of both components, making it suitable for patients needing moderate glucose control while minimizing side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Empagliflozin 12.5 mg
• Metformin Hydrochloride 500 mg

For oral administration.

Mechanism of Action

Evania M works through two complementary mechanisms:

Empagliflozin (SGLT2 inhibitor)

• Blocks sodium-glucose co-transporter 2 in the kidneys
• Reduces glucose reabsorption into the bloodstream
• Promotes excretion of excess glucose through urine
• Helps lower blood sugar levels independently of insulin

Metformin (Biguanide)

• Decreases glucose production in the liver
• Improves insulin sensitivity in muscle and fat tissues
• Reduces absorption of glucose from the intestine

Together, these actions help control both fasting and post-meal blood glucose levels effectively.

Indications

Evania M Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients inadequately controlled with single-drug therapy
• As part of a comprehensive treatment plan including diet and exercise

Dosage and Administration

• Usually taken once or twice daily with meals to reduce gastrointestinal side effects
• Dose should be individualized based on patient needs and response
• Tablets should be swallowed whole with water
• Not recommended for type 1 diabetes or diabetic ketoacidosis

Benefits

Evania M Tablet provides multiple benefits:

• Dual-action therapy improves overall blood sugar control
• Reduces fasting and postprandial glucose levels
• Supports modest weight loss (due to empagliflozin)
• Low risk of hypoglycemia when used appropriately
• May offer cardiovascular and metabolic benefits
• Convenient fixed-dose combination improves patient compliance

Possible Side Effects

Common side effects include:

• Nausea, diarrhea, or abdominal discomfort (metformin-related)
• Increased urination
• Urinary tract infections
• Genital fungal infections

Less common side effects:

• Dizziness
• Weakness
• Vitamin B12 deficiency with long-term use

Serious side effects:

• Lactic Acidosis
• Diabetic Ketoacidosis
• Kidney function impairment

Precautions

• Take the medicine with meals to reduce gastrointestinal upset
• Maintain proper hydration
• Monitor kidney function regularly
• Avoid excessive alcohol consumption
• Use cautiously in elderly patients
• Temporarily discontinue before major surgery or contrast imaging procedures

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Evania M may interact with:

• Diuretics (increased risk of dehydration)
• Insulin or sulfonylureas (risk of hypoglycemia)
• Alcohol (increased risk of lactic acidosis)
• Iodinated contrast agents

Storage

Store in a cool, dry place below 30°C, protected from moisture and light. Keep out of reach of children.