Fixcef Plus Tablet 500 mg+125 mg is a combination of Cefuroxime Axetil and Clavulanic Acid. It is a broad-spectrum antibiotic used for the treatment of various moderate to severe bacterial infections. Cefuroxime works by killing bacteria, while Clavulanic Acid helps overcome bacterial resistance by inhibiting beta-lactamase enzymes, making the antibiotic more effective.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fixcef Plus Tablet is indicated for the treatment of:

• Respiratory tract infections (sinusitis, bronchitis, pneumonia)
• Ear, nose, and throat infections (tonsillitis, otitis media)
• Urinary tract infections (UTIs)
• Skin and soft tissue infections
• Mixed or resistant bacterial infections
• Other infections caused by beta-lactamase producing organisms

Mechanism of Action

This combination works through dual mechanisms:

Cefuroxime Axetil:

• Inhibits bacterial cell wall synthesis
• Causes bacterial cell death

Clavulanic Acid:

• Inhibits beta-lactamase enzymes produced by resistant bacteria
• Protects cefuroxime from degradation
• Expands antibacterial spectrum

Together, they provide enhanced and broader antibacterial activity.

Dosage and Administration

• Usual dose: 500 mg + 125 mg twice daily or as prescribed by a physician
• Take after food for better absorption and reduced gastric discomfort
• Swallow tablet whole with water
• Do not crush or chew
• Complete the full course even if symptoms improve early

Benefits

• Broad-spectrum antibacterial coverage
• Effective against resistant bacterial strains
• Dual-action formula improves treatment success
• Suitable for respiratory, urinary, and skin infections
• Helps prevent complications of untreated infections

Possible Side Effects

Common side effects may include:

• Diarrhea
• Nausea or vomiting
• Abdominal discomfort
• Headache
• Skin rash

Less common but serious side effects:

• Severe allergic reactions
• Antibiotic-associated colitis (C. difficile infection)
• Liver enzyme abnormalities

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• Not effective against viral infections such as cold or flu
• Use cautiously in patients with penicillin or cephalosporin allergy
• Dose adjustment may be required in renal impairment
• Complete full antibiotic course
• Use only under medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Fixcef Plus Tablet may interact with:

• Anticoagulants (e.g., warfarin)
• Probenecid (may increase cefuroxime levels)
• Other antibiotics

Always inform your healthcare provider about all medicines being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.