Glifomet Tablet 5 mg+500 mg is a combination of Empagliflozin and Metformin Hydrochloride used for the management of type 2 diabetes mellitus. This dual therapy helps improve blood sugar control through complementary mechanisms—reducing glucose production in the liver and increasing glucose excretion through urine. It is used along with diet and exercise to achieve better glycemic control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Glifomet Tablet is indicated for:

• Type 2 diabetes mellitus
• Patients inadequately controlled on metformin alone
• Combination therapy for better glycemic control
• Reduction of cardiovascular risk in diabetic patients (as part of therapy plan)

Mechanism of Action

This combination works through two complementary mechanisms:

Empagliflozin (SGLT2 inhibitor):

• Blocks sodium-glucose co-transporter 2 in kidneys
• Increases urinary glucose excretion
• Lowers blood glucose levels
• May reduce weight and blood pressure

Metformin Hydrochloride (Biguanide):

• Reduces hepatic glucose production
• Improves insulin sensitivity
• Decreases intestinal glucose absorption
• Helps maintain long-term glycemic control

Dosage and Administration

• Usual dose: 5 mg + 500 mg once or twice daily or as prescribed by a physician
• Take with meals to reduce gastrointestinal discomfort
• Swallow tablet whole with water
• Dosage should be individualized based on blood glucose levels
• Regular monitoring of kidney function and blood sugar is recommended

Benefits

• Dual-action blood sugar control
• Helps lower HbA1c effectively
• May support weight reduction
• Improves insulin sensitivity
• Reduces risk of diabetes-related complications

Possible Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea
• Urinary tract infections
• Increased urination
• Abdominal discomfort

Less common but serious side effects:

• Ketoacidosis (rare but serious with SGLT2 inhibitors)
• Lactic acidosis (rare, associated with metformin)
• Dehydration or dizziness
• Genital infections

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• Use cautiously in patients with kidney impairment
• Maintain adequate hydration
• Temporarily stop during severe illness or surgery (as advised)
• Monitor blood glucose regularly
• Not recommended in type 1 diabetes

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Glifomet Tablet may interact with:

• Insulin and other antidiabetic drugs (risk of hypoglycemia)
• Diuretics (risk of dehydration)
• Alcohol (increases risk of lactic acidosis)
• Certain blood pressure medications

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.