Imruza Tablet 50 mg contains Azathioprine, an immunosuppressive medicine used to prevent organ rejection after transplantation and to treat various autoimmune diseases. It works by reducing the activity of the immune system, thereby controlling abnormal immune responses that damage the body’s own tissues.

This medicine is used under strict medical supervision due to its effects on immune function and blood cell production.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Azathioprine 50 mg

Mechanism of Action

Azathioprine is converted in the body into active metabolites that inhibit purine synthesis. This suppresses the proliferation of T and B lymphocytes, which are responsible for immune responses. By reducing immune cell activity, it helps prevent organ rejection and controls autoimmune inflammation.

Indications

Imruza Tablet 50 mg is indicated for:

• Prevention of organ transplant rejection (kidney, liver, heart)
• Rheumatoid arthritis (severe cases)
• Systemic lupus erythematosus (SLE)
• Inflammatory bowel disease (Crohn’s disease, ulcerative colitis)
• Other autoimmune disorders as prescribed

Dosage and Administration

• To be taken orally as directed by a physician
• Dose is individualized based on condition and body weight
• Usually taken once or divided into multiple doses daily
• Can be taken with or without food
• Regular monitoring of blood counts is essential

Contraindications

Imruza Tablet should not be used in:

• Known hypersensitivity to Azathioprine
• Severe bone marrow suppression
• Active serious infections
• Pregnancy (unless clearly advised by specialist)

Side Effects

Possible side effects include:

• Bone marrow suppression (low white cells, red cells, platelets)
• Nausea and vomiting
• Loss of appetite
• Increased risk of infections
• Liver function abnormalities
• Hair thinning

Precautions

• Regular complete blood count (CBC) monitoring is essential
• Use cautiously in liver or kidney impairment
• Avoid exposure to infections
• Use effective contraception during treatment
• Long-term use may increase risk of malignancy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Imruza Tablet may interact with:

• Allopurinol (increases Azathioprine toxicity)
• Other immunosuppressants (additive effects)
• Warfarin (reduced anticoagulant effect)
• Live vaccines (should be avoided)

Storage Conditions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.