Insul Injection 30% + 70% (100 IU/ml) is a premixed human insulin formulation containing Regular Human Insulin (30%) and Isophane Insulin (NPH, 70%). It is used for the effective management of diabetes mellitus by controlling both post-meal and baseline blood glucose levels. This combination provides a balanced insulin profile that helps maintain stable glycemic control throughout the day.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Regular Insulin Human 30% (short-acting)
• Isophane Insulin Human (NPH) 70% (intermediate-acting)
• Strength: 100 IU/ml

Mechanism of Action

• Regular Insulin: Works quickly to reduce postprandial (after-meal) blood glucose by promoting glucose uptake into muscle and fat cells.
• Isophane Insulin (NPH): Releases insulin gradually, providing sustained blood glucose control between meals and overnight.

Together, they mimic natural insulin secretion, offering both rapid and prolonged glycemic control in a single injection.

Indications

Insul Injection is indicated for:

• Type 1 diabetes mellitus (insulin-dependent diabetes)
• Type 2 diabetes mellitus when oral antidiabetic drugs are insufficient
• Gestational diabetes requiring insulin therapy
• Hyperglycemia management in hospitalized patients
• Patients requiring premixed insulin therapy for convenience and better compliance

Dosage and Administration

• Administered via subcutaneous injection only
• Dosage is individualized based on blood glucose levels, diet, and clinical response
• Commonly injected 30–45 minutes before meals as advised by a physician
• Injection sites include abdomen, thigh, or upper arm
• Rotate injection sites regularly to prevent tissue damage

Possible Side Effects

Common side effects include:

• Hypoglycemia (most common)
• Weight gain
• Injection site redness, swelling, or irritation
• Lipodystrophy (fat accumulation or loss at injection site)

Less common but serious effects:

• Severe hypoglycemia leading to confusion, seizures, or unconsciousness
• Allergic reactions
• Low potassium levels (hypokalemia)

Precautions

• Regular blood glucose monitoring is essential
• Do not skip meals after insulin administration
• Alcohol may increase risk of hypoglycemia
• Dose adjustment may be needed during illness, stress, or dietary changes
• Use cautiously in patients with liver or kidney impairment

Contraindications

• Hypoglycemia episodes
• Known hypersensitivity to human insulin or any component of the formulation

Drug Interactions

• Corticosteroids may increase blood glucose levels
• Beta-blockers may mask symptoms of hypoglycemia
• Oral antidiabetic agents may enhance insulin effect
• Thyroid hormones and diuretics may affect glucose control

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a refrigerator at 2°C to 8°C
• Do not freeze
• Protect from heat and direct sunlight
• Once in use, may be kept at room temperature for a limited period as per instructions

Important Notes

Insul Injection 30% + 70% (100 IU/ml) is a reliable premixed insulin therapy designed to simplify diabetes management while ensuring effective glycemic control. Proper diet, regular monitoring, and adherence to medical advice are essential for safe use.