Intafenac Eye Drop 0.10% is a sterile ophthalmic solution containing Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID), specifically formulated for ocular use. It is indicated for reducing inflammation and pain in the eye following surgical procedures or due to various ocular conditions. Intafenac acts by inhibiting enzymes responsible for inflammation, providing relief from ocular pain, swelling, and redness without the side effects associated with systemic NSAID therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Ophthalmic NSAIDs

• Anti-inflammatory & Analgesic Eye Preparations

Composition

Each milliliter of Intafenac Eye Drop 0.10% contains:

• Diclofenac Sodium: 1 mg (0.10%)

• Sterile water and ophthalmic-compatible excipients

Indications

Intafenac Eye Drop 0.10% is indicated for:

• Postoperative inflammation following cataract or ocular surgery

• Pain relief associated with ocular trauma or injury

• Management of corneal abrasions and keratitis

• Prevention of cystoid macular edema after ocular surgery

• Temporary relief of ocular pain and redness due to inflammatory eye conditions

Pharmacology

Diclofenac Sodium is a potent NSAID that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins. Prostaglandins are chemical mediators responsible for inflammation, pain, and vasodilation in ocular tissues. By blocking prostaglandin formation, Intafenac reduces ocular inflammation, edema, and discomfort, promoting faster recovery and improving visual comfort post-surgery.

Dosage & Administration

• Adults: Instill 1 drop into the affected eye 3–4 times daily, or as prescribed by the ophthalmologist.

• Duration: Usually continues for a few days to weeks, depending on the severity of inflammation and response to therapy.

• Shake well before use.

• Maintain strict aseptic technique to prevent contamination of the dropper.

Note: Avoid touching the dropper tip to the eye or surrounding surfaces.

Drug Interactions

• Caution when used with other topical ocular medications, as absorption may be altered.

• Concurrent use with systemic NSAIDs may increase the risk of additive side effects, though systemic absorption from ophthalmic use is minimal.

Contraindications

• Known hypersensitivity to diclofenac, aspirin, or other NSAIDs

• Eye infections (bacterial, viral, or fungal) unless prescribed as part of combined therapy

• Patients with corneal epithelial defects should use with caution

Side Effects

Common adverse effects may include:

• Mild burning, stinging, or irritation at the instillation site

• Conjunctival hyperemia (redness)

• Transient blurred vision

Rare but serious side effects:

• Corneal thinning or ulceration

• Delayed wound healing in postoperative eyes

• Allergic reactions, including itching, swelling, or rash

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Pregnancy & Lactation

• Pregnancy: Safety not well established; use only if clearly needed and prescribed by an ophthalmologist.

• Lactation: Limited systemic absorption; however, caution is advised when used by breastfeeding mothers.

Precautions & Warnings

• Do not exceed the recommended dose.

• Discontinue if signs of allergic reaction or corneal damage occur.

• Monitor patients with pre-existing ocular surface disease or history of corneal surgery.

• Avoid contact lens use while instilling the drops unless approved by the ophthalmologist.

Storage Conditions

• Store at 2°C–8°C (refrigerated) or as directed on the label.

• Protect from light and keep the bottle tightly closed.

• Discard after the recommended period once opened to prevent contamination.

Mechanism of Action

Diclofenac Sodium in Intafenac inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes. This reduces ocular inflammation, pain, and swelling, facilitating healing after surgery or injury and improving patient comfort.