Leo Injection 500 mg/100 ml contains Levofloxacin Hemihydrate, a broad-spectrum fluoroquinolone antibiotic used for the treatment of various bacterial infections. It is administered intravenously and is particularly useful in moderate to severe infections where oral therapy is not suitable or when rapid therapeutic action is required.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. By blocking these enzymes, Leo Injection effectively stops bacterial growth and leads to the elimination of susceptible organisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Leo Injection 500 mg/100 ml is indicated for the treatment of infections caused by susceptible bacteria, including:

• Community-acquired pneumonia

• Hospital-acquired pneumonia

• Acute bacterial sinusitis

• Acute exacerbation of chronic bronchitis

• Complicated and uncomplicated urinary tract infections

• Acute pyelonephritis

• Skin and soft tissue infections

• Chronic bacterial prostatitis

It may also be used in other serious infections as advised by a registered physician.

Dosage and Administration

Leo Injection is administered by slow intravenous infusion over a period of at least 60 minutes. The usual adult dose is 500 mg once daily, depending on the type and severity of infection. In some cases, dosing adjustments may be required based on the patient’s renal function.

The duration of therapy varies according to the clinical condition and response to treatment. Patients may be switched from intravenous to oral levofloxacin once clinically appropriate.

Always follow the prescribing physician’s instructions regarding dosage and duration of treatment.

Precautions and Warnings

• Use with caution in patients with renal impairment; dose adjustment may be necessary.

• Fluoroquinolones, including levofloxacin, may increase the risk of tendonitis and tendon rupture, particularly in elderly patients and those receiving corticosteroids.

• May cause central nervous system effects such as dizziness, confusion, or seizures in susceptible individuals.

• Should be used carefully in patients with a history of cardiac arrhythmias or those taking medications that prolong the QT interval.

• Not recommended during pregnancy and lactation unless clearly necessary and prescribed by a healthcare professional.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Nausea and vomiting

• Diarrhea

• Headache

• Insomnia

• Injection site reactions

Serious but rare side effects may include allergic reactions, severe skin reactions, tendon rupture, or changes in heart rhythm. Immediate medical attention is required if severe reactions occur.

Storage

Store below 25°C in a dry place, protected from light. Keep out of reach of children. Do not use if the solution appears discolored or contains visible particles.

Leo Injection 500 mg/100 ml offers effective and reliable intravenous antibiotic therapy for a wide range of bacterial infections, ensuring prompt and targeted treatment under medical supervision.