Leo Tablet 250 mg contains Levofloxacin Hemihydrate, a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria, making it suitable for respiratory tract infections, urinary tract infections, skin infections, and certain gastrointestinal infections. Levofloxacin works by inhibiting bacterial DNA synthesis, leading to the death of susceptible bacteria and rapid resolution of infection.

Leo Tablet 250 mg offers a convenient oral dosage, ensuring effective systemic absorption and consistent therapeutic action.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Levofloxacin Hemihydrate 250 mg

Mechanism of Action

Levofloxacin belongs to the fluoroquinolone class of antibiotics and acts by:

• Inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination

• Causing bacterial cell death (bactericidal effect)

• Providing rapid clearance of bacterial pathogens, including both Gram-positive and Gram-negative strains

Its mechanism ensures effective eradication of bacteria while reducing the risk of resistance when used as prescribed.

Indications

Leo Tablet 250 mg is indicated for the treatment of:

• Respiratory tract infections, including acute bacterial sinusitis, community-acquired pneumonia, and chronic bronchitis exacerbations

• Urinary tract infections, including complicated and uncomplicated cystitis and pyelonephritis

• Skin and soft tissue infections caused by susceptible bacteria

• Certain gastrointestinal infections, including infections caused by Salmonella or Shigella species

It is also indicated in infections where alternative antibiotics are unsuitable or ineffective.

Dosage and Administration

• The usual adult dose is 250 mg orally once daily, or as prescribed by a physician based on the infection type and severity.

• For more severe infections, the dose may be increased to 500 mg or 750 mg under medical supervision.

• Tablets should be swallowed whole with water and can be taken with or without food.

• It is essential to complete the full prescribed course to prevent recurrence and reduce the risk of bacterial resistance.

• Maintain adequate hydration during treatment to help prevent kidney complications.

Benefits

• Broad-spectrum activity against common bacterial pathogens

• Rapid symptom relief and recovery from bacterial infections

• Convenient oral formulation with high systemic bioavailability

• Effective for both mild and complicated infections

• Reduces the risk of infection progression or complications

Precautions

• Use cautiously in patients with kidney impairment, as dosage adjustment may be required

• Avoid excessive sunlight exposure, as fluoroquinolones may cause photosensitivity

• Not recommended for children, pregnant, or breastfeeding women unless specifically prescribed

• Inform your doctor of other medications to avoid interactions, especially with antacids, iron supplements, or other drugs that may affect Levofloxacin absorption

• Monitor for signs of tendon inflammation or rupture, a rare but serious side effect

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea

• Headache

• Dizziness or mild fatigue

• Abdominal pain

Rare but serious side effects:

• Tendon rupture or tendonitis

• Peripheral neuropathy (nerve pain or tingling)

• Severe allergic reactions

• Heart rhythm disturbances (QT prolongation)

Seek medical attention immediately if severe reactions, tendon pain, or unusual neurological symptoms occur.

Storage

Store below 30°C in a cool, dry place, away from light and moisture. Keep out of reach of children.