Nasomet 50 mcg/Spray Nasal Spray is a corticosteroid nasal preparation containing mometasone furoate monohydrate, designed to provide effective relief from nasal inflammation and allergic symptoms. It is widely used in the management of allergic rhinitis and nasal polyps due to its strong anti-inflammatory action and minimal systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nasomet 50 mcg/Spray is indicated for:

• Treatment of nasal symptoms of seasonal allergic rhinitis

• Treatment of nasal symptoms of perennial allergic rhinitis

• Prophylaxis of seasonal allergic rhinitis symptoms

• Treatment of nasal polyps

It is suitable for use in:

• Adults and children 2 years of age and older for allergic rhinitis

• Adults and adolescents 12 years and older for prophylaxis of seasonal allergic rhinitis

• Adults 18 years and older for nasal polyps

Therapeutic Class

• Nasal Steroid Preparations

Pharmacology

Nasomet contains mometasone furoate, a potent corticosteroid with marked anti-inflammatory properties. Although the exact mechanism of action in allergic rhinitis is not fully understood, corticosteroids are known to inhibit multiple inflammatory pathways. They act on various inflammatory cells such as mast cells, eosinophils, neutrophils, macrophages, and lymphocytes, and suppress the release of inflammatory mediators including histamines, leukotrienes, cytokines, and eicosanoids.

Nasomet demonstrates high protein binding (approximately 98–99%) within the concentration range of 5–500 ng/mL. The effective plasma elimination half-life is around 5.8 hours, contributing to its sustained local action with low systemic exposure.

Dosage and Administration

Allergic Rhinitis

• Adults and children ≥12 years:
  Two sprays (50 mcg per spray) in each nostril once daily (total daily dose: 200 mcg).

• Children 2–11 years:
  One spray (50 mcg) in each nostril once daily (total daily dose: 100 mcg).

For patients with predictable seasonal allergens, prophylactic treatment is recommended 2–4 weeks before the onset of the pollen season.

Nasal Polyps (Adults ≥18 years):

• Two sprays in each nostril twice daily (total daily dose: 400 mcg).

• Some patients may respond adequately to two sprays in each nostril once daily (200 mcg/day).

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• No clinically significant drug interactions have been reported with Nasomet 50 mcg/Spray.

Contraindications

• Known hypersensitivity to mometasone furoate or any component of the formulation.

Side Effects

Nasomet is generally well tolerated. Mild side effects may include:

• Headache

• Viral infections

• Sore throat

• Epistaxis (nosebleeds)

• Cough

Pregnancy and Lactation

There are no adequate and well-controlled studies in pregnant women. Nasomet should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether mometasone is excreted in human milk; therefore, caution is advised when administered to breastfeeding women.

Precautions and Warnings

Caution is required in patients with:

• Active or latent tuberculosis

• Untreated fungal, bacterial, or systemic viral infections

• Ocular herpes simplex

Long-term use should be monitored as with other nasal corticosteroids.

Overdose

Due to low systemic bioavailability, overdose is unlikely to cause significant systemic effects. No specific treatment is required other than observation.

Storage Conditions

Store below 30°C, protected from light and moisture. Keep out of reach of children.