Olmevas HZ Tablet 40 mg+12.5 mg is a combination antihypertensive medicine containing Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide, a thiazide diuretic. It is used for the treatment of high blood pressure (hypertension), especially in patients who require stronger blood pressure control than single-agent therapy. This combination helps relax blood vessels and reduce excess fluid in the body, leading to effective and sustained blood pressure reduction.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Olmesartan Medoxomil 40 mg
• Hydrochlorothiazide 12.5 mg

Mechanism of Action

Olmesartan Medoxomil blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and reducing vascular resistance, which lowers blood pressure.

Hydrochlorothiazide increases urinary excretion of sodium and water, reducing blood volume and further lowering blood pressure.

Together, they provide a dual mechanism of action that improves blood pressure control and enhances cardiovascular protection.

Indications

Olmevas HZ Tablet 40 mg+12.5 mg is indicated for:

• Essential hypertension (moderate to severe cases)
• Patients not adequately controlled with monotherapy
• Combination therapy for long-term blood pressure management
• Reduction of risk of cardiovascular events such as stroke and heart attack

Dosage and Administration

• Take exactly as prescribed by a healthcare professional.
• Usually taken once daily at the same time each day.
• Can be taken with or without food.
• Swallow the tablet whole with water; do not crush or chew.
• Do not discontinue without medical advice, even if symptoms improve.

Benefits

• Provides strong dual-action blood pressure control
• Helps maintain stable 24-hour BP levels
• Reduces risk of stroke, heart attack, and kidney complications
• Effective in patients resistant to single therapy
• Helps reduce fluid retention and swelling

Side Effects

Common side effects may include:

• Dizziness
• Headache
• Increased urination
• Fatigue
• Nausea

Serious but rare side effects:

• Electrolyte imbalance (low potassium, sodium)
• Dehydration or low blood pressure
• Kidney function impairment
• Increased uric acid levels (may trigger gout)
• Allergic reactions

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Not recommended during pregnancy due to risk of fetal harm.
• Use cautiously in patients with kidney, liver, or heart disease.
• Regular monitoring of blood pressure, kidney function, and electrolytes is advised.
• Avoid potassium supplements unless prescribed.
• May cause dizziness; caution while driving or operating machinery.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Olmevas HZ Tablet may interact with:

• Other antihypertensive medicines
• Diuretics and lithium
• NSAIDs (may reduce antihypertensive effect)
• Potassium supplements or potassium-sparing agents
• Corticosteroids

Always inform your healthcare provider about all medicines being used.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.