Alodia Tablet 12.5 mg contains Alogliptin Benzoate, an oral antidiabetic medicine used in the management of type 2 diabetes mellitus. It belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by improving the body’s natural regulation of blood glucose levels. Alodia Tablet 12.5 mg is particularly useful for patients who require a lower dose due to renal impairment or as part of combination therapy. It is prescribed alongside proper diet and exercise to help maintain long-term glycemic control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Alodia Tablet 12.5 mg is indicated for:

• Treatment of type 2 diabetes mellitus in adults

• Improving glycemic control when diet and exercise alone are inadequate

• Use as monotherapy or in combination with other antidiabetic agents, including metformin, sulfonylureas, thiazolidinediones, or insulin

This medication is not intended for use in type 1 diabetes mellitus or diabetic ketoacidosis.

Therapeutic Class

DPP-4 inhibitor (Antidiabetic agent)

Pharmacology

Alogliptin Benzoate selectively inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), which breaks down incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By inhibiting DPP-4, alogliptin increases endogenous incretin levels, leading to enhanced glucose-dependent insulin secretion and decreased glucagon release. This reduces hepatic glucose production and improves both fasting and postprandial blood glucose levels. Because its action depends on blood glucose levels, the risk of hypoglycemia is minimal when used alone.

Dosage and Administration

The dosage of Alodia Tablet 12.5 mg should be determined by a physician based on the patient’s clinical condition.

• Recommended dose: 12.5 mg once daily

• May be taken with or without food

• Swallow the tablet whole with water

This strength is commonly prescribed for patients with moderate renal impairment. Dose adjustments may be necessary depending on kidney function, and regular monitoring is advised.

Drug Interactions

Alogliptin has a low likelihood of clinically significant drug interactions. It can be used with most oral antidiabetic medicines and insulin. However, when combined with insulin or insulin secretagogues, there may be an increased risk of hypoglycemia, and dose adjustment of the concomitant drug may be required.

Contraindications

Alodia Tablet 12.5 mg is contraindicated in patients with known hypersensitivity to Alogliptin Benzoate or any excipients in the formulation. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis.

Side Effects

Alodia Tablet is generally well tolerated. Common side effects may include headache, upper respiratory tract infection, nasopharyngitis, and mild gastrointestinal discomfort. Rare but serious adverse reactions include pancreatitis, severe joint pain, and hypersensitivity reactions such as angioedema or skin rash.

Precautions and Warnings

Caution is advised in patients with renal impairment, a history of pancreatitis, or heart failure. Renal function should be assessed before starting therapy and monitored periodically. Patients should be advised to seek medical attention if they experience severe abdominal pain suggestive of pancreatitis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy and Lactation

There is limited data on the use of Alogliptin during pregnancy and breastfeeding. Alodia Tablet 12.5 mg should be used only if the potential benefit justifies the potential risk, under medical supervision.

Storage Conditions

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.