Prelica CR Tablet 165 mg contains Pregabalin in a controlled-release (CR) formulation. It is designed to provide sustained release of the medicine over an extended period, allowing for once-daily dosing and more stable blood levels.

Pregabalin is commonly used to manage neuropathic (nerve) pain, fibromyalgia, and as adjunctive therapy in partial-onset seizures. The controlled-release formulation helps improve convenience and may enhance patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Prelica CR 165 mg is indicated for:

• Peripheral neuropathic pain (e.g., diabetic neuropathy, post-herpetic neuralgia)

• Central neuropathic pain

• Fibromyalgia

• Adjunctive treatment of partial-onset seizures (as per physician’s guidance).

Dosage and Administration

• The usual dose is determined by the physician based on the patient’s condition and response.

• Typically taken once daily, preferably after an evening meal.

• Swallow the tablet whole with water.

• Do not crush, chew, or break the tablet.

• Dose adjustment is required in patients with renal impairment.

Do not discontinue suddenly; taper gradually under medical supervision.

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This action reduces the release of excitatory neurotransmitters such as glutamate and substance P, helping to decrease abnormal nerve signaling responsible for pain and seizures.

The controlled-release formulation ensures gradual absorption and prolonged therapeutic effect.

Benefits

• Once-daily convenient dosing

• Sustained pain control

• Reduced fluctuations in blood levels

• Effective for chronic neuropathic pain conditions

• May improve sleep disturbances related to nerve pain

Safety Information

Contraindications

• Hypersensitivity to pregabalin

Warnings and Precautions

• May cause dizziness and drowsiness

• Avoid driving or operating machinery until the effects are known

• Monitor for mood changes or suicidal thoughts

• Use cautiously in elderly patients

• Risk of dependence with prolonged use

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Common Side Effects

• Dizziness

• Drowsiness

• Blurred vision

• Dry mouth

• Weight gain

• Peripheral edema

Avoid alcohol, as it may enhance central nervous system side effects.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.